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Related Experiment Video

Updated: Jun 8, 2026

A Mouse Ear Model for Allergic Contact Dermatitis Evaluation

A Mouse Ear Model for Allergic Contact Dermatitis Evaluation

Published on: March 24, 2023

Eyeglass allergic contact dermatitis.

Kimberly Scott¹, Michelle M Levender, Steven R Feldman

¹Department of Dermatology, Center for Dermatology Research, Wake Forest University School of Medicine, Winston-Salem, North Carolina, USA.

Dermatology Online Journal

|September 30, 2010

Summary

This summary is machine-generated.

Allergic contact dermatitis can be diagnosed by the pattern of a rash. This case highlights how facial redness from eyeglasses can indicate an allergic reaction to frame materials.

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Area of Science:

Dermatology
Allergology
Toxicology

Background:

Allergic contact dermatitis (ACD) is a prevalent T-cell-mediated skin reaction.
Identifying the causative allergen is crucial for managing ACD.
Characteristic eruption patterns aid in diagnosing specific allergens.

Observation:

A patient presented with distinct red plaques on the face.
The morphology and distribution of the rash were key diagnostic clues.
The pattern strongly suggested contact with eyeglasses.

Findings:

Eyeglass frames are frequently manufactured using materials that can act as allergens.
Specific components within eyeglass frames can trigger allergic contact dermatitis.
The facial distribution of the rash correlated with contact points from eyeglasses.

Implications:

Recognizing the link between eyeglasses and facial ACD is clinically valuable.
Dermatologists should consider eyeglass allergens in patients with characteristic facial rashes.
Prompt identification can lead to effective allergen avoidance and treatment.