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Related Concept Videos

Irritable Bowel Syndrome01:23

Irritable Bowel Syndrome

DefinitionIrritable bowel syndrome (IBS) is a functional gastrointestinal disorder characterized by recurrent combinations of abdominal pain, bloating, diarrhea, or constipation.Pathophysiology of irritable bowel syndromeIts pathophysiology is multifactorial, involving disturbances in motility, sensory processing, microbial balance, barrier integrity, and gut–brain communication. These mechanisms interact to produce symptoms that vary across IBS subtypes.Altered Motility PatternsDisordered...
Irritable Bowel Syndrome III: Medical and Nursing Management01:30

Irritable Bowel Syndrome III: Medical and Nursing Management

Managing Irritable Bowel Syndrome (IBS) involves a multifaceted approach, including lifestyle modifications, dietary changes, and medication.
Bipolar Disorder01:30

Bipolar Disorder

Bipolar disorder is a chronic mental health condition marked by significant mood fluctuations, including episodes of mania and depression. Elevated energy levels, heightened mood or irritability, impulsive behavior, reduced sleep needs, rapid speech, racing thoughts, inflated self-esteem, and distractibility characterize mania. Individuals with bipolar disorder often alternate between depressive and manic states, with periods of emotional stability lasting an average of six months to a year.
Bulimia Nervosa01:30

Bulimia Nervosa

Bulimia nervosa is a complex and severe eating disorder characterized by a cyclical pattern of binge-and-purge eating pattern. It generally involves an episode of binge eating, followed by compensatory behaviors such as vomiting, excessive exercise, laxative use, or fasting, to prevent weight gain. Despite often maintaining a normal weight, individuals with bulimia are intensely preoccupied with their body image and harbor an overwhelming fear of gaining weight. This can contribute to the...
Irritable Bowel Syndrome I: Introduction01:17

Irritable Bowel Syndrome I: Introduction

Irritable Bowel Syndrome (IBS) is characterized by functional disturbances in the gastrointestinal system, presenting a cluster of symptoms without evident structural or biochemical abnormalities. It primarily affects the large intestine and may cause abdominal pain, bloating, excessive gas, diarrhea, constipation, or both.
IBS is a chronic condition that can persist over a long period or recur frequently.
The pathogenesis of IBS involves a complex interplay of the following factors:
Altered...
Irritable Bowel Syndrome II: Clinical Features and Diagnostic Evaluation01:30

Irritable Bowel Syndrome II: Clinical Features and Diagnostic Evaluation

Irritable Bowel Syndrome II: Clinical Features and Diagnostic Evaluation
Irritable Bowel Syndrome (IBS) is classified into subtypes based on the predominant bowel habits as determined by the Bristol Stool Form Scale (BSFS). The subtypes are:

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Updated: Jun 8, 2026

Developing a Rat Model for Bipolar Disorder
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Developing a Rat Model for Bipolar Disorder

Published on: May 2, 2025

Binswanger disease--an update.

Louis R Caplan1, Joao A Gomes

  • 1Beth Israel Deaconess Medical Center, Boston, MA 02215, USA. lcaplan@bidmc.harvard.edu

Journal of the Neurological Sciences
|September 30, 2010
PubMed
Summary
This summary is machine-generated.

Binswanger disease, a common cause of elderly vascular dementia, is updated here. This report details pathological and clinical findings, imaging, and diagnosis for this condition.

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Abbiategrasso Brain Bank Protocol for Collecting, Processing and Characterizing Aging Brains
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Last Updated: Jun 8, 2026

Developing a Rat Model for Bipolar Disorder
04:42

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Published on: May 2, 2025

Abbiategrasso Brain Bank Protocol for Collecting, Processing and Characterizing Aging Brains
12:28

Abbiategrasso Brain Bank Protocol for Collecting, Processing and Characterizing Aging Brains

Published on: June 3, 2020

Area of Science:

  • Neurology
  • Geriatrics
  • Radiology

Background:

  • Binswanger disease is a frequent cause of vascular dementia in older adults.
  • It is characterized by white matter changes in the brain.

Purpose of the Study:

  • To provide an updated overview of Binswanger disease.
  • To highlight recent advancements in its pathological and clinical identification, imaging, and diagnosis.

Main Methods:

  • Review of current literature on Binswanger disease.
  • Emphasis on recent diagnostic and imaging techniques.

Main Results:

  • Updated pathological and clinical features of Binswanger disease.
  • Discussion of advanced imaging modalities for identification.
  • Current diagnostic criteria and approaches.

Conclusions:

  • Binswanger disease diagnosis and management require updated knowledge.
  • Recent advances in imaging improve early detection and characterization.