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Related Concept Videos

Biological Causes of Schizophrenia01:29

Biological Causes of Schizophrenia

Schizophrenia, a severe psychiatric disorder, arises from a complex interplay of biological factors, including genetic predisposition, structural brain abnormalities, neurotransmitter dysregulation, and developmental irregularities. These factors collectively contribute to the onset and progression of the disorder, which typically manifests in late adolescence or early adulthood.
Genetic Factors in Schizophrenia
The genetic basis of schizophrenia is strongly supported by family and twin studies.
Psychosis: Pathophysiology of Schizophrenia and Other Psychotic Disorders01:27

Psychosis: Pathophysiology of Schizophrenia and Other Psychotic Disorders

Schizophrenia is a neurodevelopmental disorder whose origins are rooted in complex genetic components. Despite our burgeoning understanding, the pathophysiology of this disorder remains incompletely deciphered.
Researchers have identified genetic factors that increase susceptibility to schizophrenia, underscoring the intricate interplay between genetics and environment in disease development. At the core of schizophrenia's pathophysiology is excessive dopaminergic neurotransmission within the...
Positive Symptoms of Schizophrenia: Hallucinations and Delusions01:30

Positive Symptoms of Schizophrenia: Hallucinations and Delusions

Schizophrenia is a complex mental health disorder that can manifest with various positive symptoms, including thought, movement, and behavior disorders. These symptoms significantly disrupt cognitive and motor functions, leading to profound effects on an individual's ability to engage with the world.
Thought Disorders
Disorganized and unusual thought processes mark thought disorders in schizophrenia. One key feature is disorganized speech, where an individual's conversation includes loosely...
Psychological and Sociocultural Causes of Schizophrenia01:29

Psychological and Sociocultural Causes of Schizophrenia

Schizophrenia, a complex psychiatric disorder, has been historically misunderstood. Early psychological theories attributed its origins to childhood trauma and unresponsive parenting. However, contemporary research largely rejects these notions, favoring the vulnerability-stress hypothesis. This model proposes that individuals with a genetic predisposition to schizophrenia may develop the disorder following exposure to significant environmental stressors. Notably, studies on high-risk...
Schizophrenia01:17

Schizophrenia

Schizophrenia, a term introduced by Swiss psychiatrist Eugen Bleuler in 1911, describes a severe psychological disorder marked by profound disruptions in attention, thought processes, language, emotion, and interpersonal relationships. The core feature of schizophrenia is psychosis — a state characterized by a fundamental detachment from reality. This disconnection manifests through distorted logic, impaired perception, and atypical behavior, severely affecting the lives of those diagnosed.
Negative and Cognitive Symptoms of Schizophrenia01:30

Negative and Cognitive Symptoms of Schizophrenia

Negative symptoms of schizophrenia indicate a reduction or absence of typical behaviors and emotional responses found in healthy individuals, while positive symptoms reflect an excess or distortion of normal functioning.
Negative Symptoms
Negative symptoms of schizophrenia manifest as deficits in normal emotional and behavioral functioning, profoundly impacting daily life. Individuals with schizophrenia often display a flat affect, characterized by a near-total absence of emotional expression,...

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Methods to Explore the Influence of Top-down Visual Processes on Motor Behavior
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When predictive mechanisms go wrong: disordered visual synchrony thresholds in schizophrenia.

Laurence Lalanne1, Mitsouko van Assche, Anne Giersch

  • 1INSERM U666, Centre Hospitalier Régional Universitaire de Strasbourg, Department of Psychiatry I, Hôpital Civil 1, place de l'Hôpital, F-67091Strasbourg Cedex, France.

Schizophrenia Bulletin
|September 30, 2010
PubMed
Summary
This summary is machine-generated.

Patients with schizophrenia have an enlarged time window for perceiving simultaneous events. This suggests impaired predictive mechanisms, leading to a reactive processing of temporal information.

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Area of Science:

  • Cognitive Neuroscience
  • Psychiatry
  • Temporal Perception

Background:

  • Schizophrenia is associated with impaired temporal continuity perception.
  • Patients often judge asynchronous events as simultaneous, even with significant onset asynchronies.

Purpose of the Study:

  • To investigate whether schizophrenia's temporal perception deficit involves event fusion or a deficit in coding time-event structure.
  • To explore the underlying mechanisms of altered temporal processing in schizophrenia.

Main Methods:

  • Utilized the Simon effect to implicitly assess temporal asynchrony processing.
  • Participants judged simultaneity of two squares presented asynchronously.
  • Response biases were analyzed based on stimulus presentation side and asynchrony.

Main Results:

  • Patients with schizophrenia exhibited an enlarged temporal window for simultaneity judgments.
  • Patients showed a reversed Simon effect, with responses biased towards the first square under specific conditions.
  • Control participants consistently showed a bias towards the second square.

Conclusions:

  • Schizophrenia is characterized by an impaired ability to predict event sequences, unlike controls who utilize predictive mechanisms.
  • Patients appear to process events as isolated rather than sequential, relying on reactive mechanisms.
  • This deficit in predictive temporal coding contributes to the altered perception of time in schizophrenia.