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Related Concept Videos

Skin Cancer01:30

Skin Cancer

Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
Staphylococcal Skin Infections01:29

Staphylococcal Skin Infections

Staphylococcus aureus is a Gram-positive coccus that resides harmlessly on the skin and mucous membranes of healthy individuals. When the skin barrier is breached, it can shift from a commensal to an opportunistic pathogen. This transition is facilitated by surface adhesins, such as clumping factor B and S. aureus surface protein G (SasG), which bind to structural proteins, including loricrin and cytokeratin, in the damaged epidermis. Protein A, another key factor, binds the Fc region of...
Skin Diseases and Disorders01:23

Skin Diseases and Disorders

Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
Pulmonary Tuberculosis III01:31

Pulmonary Tuberculosis III

Tuberculosis (TB) is a contagious infection primarily affecting the lung parenchyma but which can also affect other body parts. TB can be classified based on disease development, presentation, and the affected anatomical site.
The first classification is based on the development of the disease, and it includes the following categories:
Reticular Dermis01:15

Reticular Dermis

The papillary and reticular dermis are the two layers of the dermis. They are made of connective tissue with fibers of collagen extending from one to the other, making the border between the two somewhat indistinct. The dermal papillae extending into the epidermis belong to the papillary layer, whereas the dense collagen fiber bundles below belong to the reticular layer.
Reticular Layer
Underlying the papillary layer is the much thicker reticular layer, composed of dense, irregular connective...
Rocky Mountain Spotted Fever01:26

Rocky Mountain Spotted Fever

Rocky Mountain Spotted Fever (RMSF) is a severe tick-borne illness caused by Rickettsia rickettsii, a Gram-negative, coccobacillary bacterium. This pathogen is an obligate intracellular parasite, requiring a host cell for replication. Transmission occurs through the bite of an infected tick. In the United States, the most important vectors are Dermacentor variabilis (American dog tick) and Dermacentor andersoni (Rocky Mountain wood tick), though other tick species may also serve as vectors.

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Related Experiment Video

Updated: Jun 8, 2026

Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease
04:44

Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease

Published on: June 16, 2020

Cutaneous sarcoidosis without systemic involvement.

G Singh1, P Sangolli, K Dash

  • 1Department of Dermatology and STD, Command Hospital (Air Force) Bangalore - 560007, India.

Indian Journal of Dermatology, Venereology and Leprology
|September 30, 2010
PubMed
Summary
This summary is machine-generated.

This case report details a 49-year-old woman with cutaneous sarcoidosis. The patient showed no signs of systemic sarcoidosis involvement, highlighting a localized presentation.

Related Experiment Videos

Last Updated: Jun 8, 2026

Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease
04:44

Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease

Published on: June 16, 2020

Area of Science:

  • Dermatology
  • Internal Medicine
  • Pathology

Background:

  • Sarcoidosis is a multisystem inflammatory disease.
  • Cutaneous involvement is common but often occurs with systemic disease.
  • Localized cutaneous sarcoidosis without systemic involvement presents diagnostic challenges.

Purpose of the Study:

  • To report a case of a 49-year-old woman with exclusive cutaneous sarcoidosis.
  • To emphasize the importance of considering localized forms of sarcoidosis.
  • To discuss diagnostic and management considerations for cutaneous sarcoidosis.

Main Methods:

  • Clinical presentation and dermatological examination.
  • Diagnostic workup including imaging and laboratory tests to rule out systemic involvement.
  • Histopathological examination of skin biopsy.

Main Results:

  • The patient presented with characteristic skin lesions of sarcoidosis.
  • Extensive investigations confirmed the absence of any systemic sarcoidosis.
  • Skin biopsy revealed non-caseating granulomas consistent with sarcoidosis.

Conclusions:

  • Cutaneous sarcoidosis can occur in isolation without systemic manifestations.
  • Early recognition and diagnosis are crucial for appropriate management.
  • This case underscores the diverse clinical spectrum of sarcoidosis.