An open trial of pentoxifylline in schamberg's disease

Fifteen patients with Schamberg's disease were enrolled in the study. Each patient was given 400mg of pentoxifylline once a day for 8 weeks. Skin biopsy was done in 6 patients to document the disease. Pretreatment and post treatment evaluation were made. There was no objective improvement in any of the patients though 4 reported subjective improvement in their pigmentation.