A study of the therapeutic efficacy of various regimes in chronic urticaria

A total of sixty patients with chronic urticaria (>3 months duration) were divided into three groups. Group A - was treated once daily with tab loratadine 10 mg. Group B- with cetrizine 10 mg and Group C - with tab fexofenadine hydrochloride 180 mg. Total duration of treatment was 4 weeks. Pre and Post treatment evaluation were made. It was observed that loratadine was superior to all, cetrizine was second and fexofenadine was third regarding over all clinical efficacy, while side effects like sedation was maximum observed in nine cases, with cetrizine, No side effects were observed with the other two regimens.