Related Experiment Video
Updated: Jun 8, 2026

Improving IV Insulin Administration in a Community Hospital
Published on: June 11, 2012
Insights from a large observational database of continuous glucose monitoring adoption, insulin pump usage and
John B Welsh1, Brian Kannard, Keith Nogueira
1Medtronic, Inc., 18000 Devonshire Street, Northridge, CA 91325, USA. john.b.welsh@medtronic.com
Objective:
The CareLink™ (Medtronic, Inc., Northridge, CA) database houses data from continuous glucose monitoring (CGM), insulin pumps, and blood glucose (BG) meters. This study examined CGM usage and its relationship to insulin delivery and glycemia in CareLink users with type 1 diabetes mellitus (T1DM).
Methods:
Users whose CareLink accounts contained =120 days of pump and glucose readings within a 180-day interval were further selected and stratified based on the frequency of CGM use and adequacy of glycemic control; correlations between these variables were sought.
Results:
The proportion of subjects with pre-specified favorable glycemic parameters rose with increasing sensor use (p<0.001). These subjects administered more and smaller boluses, gave a higher proportion of their total daily dose (TDD) of insulin as boluses, and maintained lower TDDs than those with pre-specified less-favorable glycemic parameters (all p<0.001).
Conclusions:
A favorable dose effect of CGM use was evident. CGM data facilitates smaller and more frequent bolus dosing, allowing for improved glycemic control.
Related Concept Videos
Nursing Clinical Information System
A Nursing Clinical Information System (NCIS) is a specialized type of healthcare information system tailored to meet the unique needs of nursing practice. It incorporates the principles of nursing informatics to streamline information management and improve the quality of care delivery.
Critical attributes of NCIS include:
Diabetes: Management and Pharmacotherapy
Insulin remains the cornerstone of treatment for most patients with type 1 and many...
Insulin: Dosing Regimen and Adverse Effects
The basal dose constitutes about 40%-50% of the total daily dose, with the rest as premeal insulin. The mealtime insulin dose should mirror...
Pulse rhythm
Conversely, an irregular pulse pattern is termed dysrhythmia, stemming from disruptions in cardiac muscle...
Hypoglycemia
Glucose Homeostasis: Pancreatic Islets and Insulin Secretion
Insulin and C-peptide are co-secreted in...
