Merkel cell carcinoma in a kidney transplant patient: Case report and update on management

Merkel cell carcinoma (MCC) is a rare, aggressive neuroendocrine tumor. Its incidence is markedly greater in immunocompromised patients. MCC is found almost exclusively on sun-exposed facial sites.

We describe a case of a 62-year-old male renal transplant recipient who was diagnosed with MCC with primary atypical localization on the buttock 5 years after transplantation. Despite the conversion from CsA to mTOR inhibitor, surgical operation, and radiotherapy, the patient developed disseminated skin lesions and died due to multiple metastases.

This case emphasizes the importance of screening for MCC in atypical localizations in transplant organ recipients.