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Detrusor Underactivity Model in Rats by Conus Medullaris Transection
Published on: August 28, 2020
Medical management of overactive bladder
Sarvpreet S Ubee1, Ramaswamy Manikandan, Gurpreet Singh
1Department of Urology, Royal Liverpool University Hospital, Liverpool, United Kingdom.
Indian Journal of Urology : IJU : Journal of the Urological Society of India
|September 30, 2010
Summary
Overactive bladder (OAB) affects 12-17% in Europe and 17% in the US, with higher prevalence in Asia. Treatments include lifestyle changes, bladder training, and medications like antimuscarinics.
Area of Science:
- Urology
- Geriatrics
- Public Health
Background:
- Overactive bladder (OAB) is a common condition characterized by urinary urgency, frequency, and nocturia.
- OAB syndrome affects a significant portion of the population globally, with reported incidence rates varying by region.
Purpose of the Study:
- To provide an overview of Overactive Bladder (OAB) syndrome.
- To discuss the incidence, causes, diagnosis, and management of OAB.
Main Methods:
- Review of existing literature and epidemiological data on OAB.
- Summary of diagnostic criteria and treatment approaches for OAB.
Main Results:
- OAB incidence ranges from 12-17% in Europe and 17% in the US, with a higher prevalence of 53.1% reported in Asia.
- Idiopathic detrusor overactivity accounts for approximately 75% of OAB cases; other causes include neurological disease and bladder outflow obstruction.
- First-line treatments include lifestyle modifications, bladder training, pelvic floor muscle exercises, and anticholinergic drugs.
Conclusions:
- OAB is a prevalent condition with diverse etiologies.
- Effective management strategies, including non-pharmacological and pharmacological therapies, are available for OAB symptoms.
- Antimuscarinics are a primary pharmacological choice for OAB, offering proven efficacy with varying side effect profiles.
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