Clinical evaluation of postoperative sensitivity using self-etching adhesives containing glutaraldehyde

Area of Science:

• Dentistry
• Dental Materials Science
• Clinical Research

Background:

• Postoperative sensitivity (POS) is a common concern following dental restorations.
• Dental adhesive systems play a crucial role in bonding restorative materials and may influence POS.
• Glutaraldehyde-containing agents are utilized in some adhesive systems for their potential desensitizing properties.

Purpose of the Study:

• To compare the incidence of postoperative sensitivity (POS) at 48 hours and seven days.
• To evaluate POS in occlusal restorations bonded with three distinct adhesive systems: Adper SBMP-Plus (SBMP), Gluma Comfort One Bond + Desensitizer (GC+D), and I Bond (IB).
• To assess the influence of glutaraldehyde-containing adhesives on POS.

Main Methods:

• A clinical study involving occlusal restorations using three adhesive systems: SBMP (three-step etch-and-rinse), GC+D (two-step etch-and-rinse), and IB (all-in-one self-etching/priming).
• All restorations were placed using Filtek Supreme nanoparticle composite resin.
• Postoperative sensitivity was evaluated at 48 hours and seven days post-procedure. Data were analyzed using the non-parametric Friedman test.

Main Results:

• No statistically significant differences in postoperative sensitivity (POS) were observed among the three tested adhesive groups.
• POS levels were comparable between the SBMP, GC+D, and IB adhesive systems at both the 48-hour and seven-day evaluation points.
• The presence of glutaraldehyde in GC+D and IB did not lead to a significant reduction in POS compared to SBMP.

Conclusions:

• The choice among the evaluated adhesive systems (SBMP, GC+D, IB) did not significantly impact postoperative sensitivity in occlusal restorations.
• Glutaraldehyde-containing adhesives (GC+D, IB) did not demonstrate a significant advantage in reducing postoperative sensitivity compared to the non-glutaraldehyde containing system (SBMP).
• Further research may explore long-term sensitivity and other clinical parameters associated with these adhesive systems.