Related Experiment Videos
Effect of Cd2+ on ATP synthesis coupled to electron transfer in cadmium-resistant and -sensitive Staphylococcus
1Department of Pharmaceutical Microbiology, Medical Academy, Lublin, Poland.
Acta Biochimica Polonica
|January 1, 1990
Abstract:
In the Cd2(+)-resistant Staphylococcus aureus 17810R which contains the plasmid-coded Cd2+ efflux system, accumulation of Cd2+ was highly reduced. Consequently, neither respiration nor ATP synthesis coupled to electron transfer were inhibited. The plasmidless S. aureus strain 17810S accumulated Cd2+ via the Mn2+ porter down the membrane potential (delta phi) which resulted in inhibition of respiration and of ATP synthesis.