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Anti-HCV prevalence among diabetic and non-diabetic Egyptian children

H El-Karaksy1, G H Anwar, M S El-Raziky

  • 1Department of Pediatrics, Cairo University, Cairo, Egypt.

Current Diabetes Reviews
|October 1, 2010
PubMed

Insights

Hepatitis C virus (HCV) infection prevalence was similar in children with type 1 diabetes and non-diabetic children. Standard infection control measures can prevent HCV spread in pediatric diabetes units, even in high-prevalence areas like Egypt.

Area of Science:

  • Pediatric Endocrinology
  • Infectious Diseases
  • Hepatology

Background:

  • Type 1 diabetes (T1DM) management involves frequent medical interventions, raising concerns about potential infection transmission.
  • Hepatitis C virus (HCV) is a significant public health concern, particularly in Egypt, a country with a high HCV burden.

Purpose of the Study:

  • To determine the prevalence of HCV infection in children with T1DM compared to non-diabetic children.
  • To investigate potential risk factors for HCV infection in these pediatric populations.

Main Methods:

  • A comparative study involving 692 children with T1DM and 1042 non-diabetic children from Cairo University Pediatric Hospital.
  • Screening for anti-HCV antibodies using third-generation ELISA.
  • Assessment of exposure to medical care, personal hygiene practices, and environmental factors.

Main Results:

  • Anti-HCV antibody prevalence was comparable between diabetic (2.5%) and non-diabetic (1.4%) children below 9 years of age (p=0.25).
  • Children with T1DM showed higher exposure to medical care, including daily insulin injections and blood glucose monitoring (p=0.04).
  • Non-diabetic children reported higher exposure to shared razors (p=0.05) and traditional haircutting practices (p=0.05).

Conclusions:

  • HCV prevalence is similar in young children with and without type 1 diabetes.
  • Implementing standard infection control precautions is effective in preventing HCV transmission within pediatric diabetes units.
  • The findings underscore the importance of infection control in managing T1DM in high HCV prevalence settings.

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