Related Experiment Video
Updated: Jun 8, 2026

A Neonatal Imaging Model of Gram-Negative Bacterial Sepsis
Published on: August 12, 2020
[A neonatal case of immunoallergic acute interstitial nephritis]
A Essid1, N Allani-Essid, R Rubinsztajn
1Service de réanimation pédiatrique, hôpital Raymond-Poincaré, Assistance publique-Hôpitaux de Paris, 104, boulevard Raymond-Poincaré, 92380 Garches, France. aben.essid@rpc.aphp.fr
Abstract:
Acute interstitial nephritis accounts for about 10 % of the cases of acute renal failure. An adverse drug reaction caused by an immunoallergic mechanism is suggested when fever, skin rash, eosinophilia, and eosinophiluria are associated. The outcome is favorable after withdrawal of drug therapy in most cases. We report a case of acute interstitial nephritis induced by immunoallergic drug mechanisms, in a 3-week-old infant who presented with acute renal failure associated with eosinophilia and hepatitis and who had received cefotaxime and gentamicin. The patient's progression was favorable with normalization of renal and liver function 1 week after suspension of antibiotic drugs.
Related Concept Videos
Acute Pyelonephritis I: Introduction
Nephrotic Syndrome I : Introduction
Acute Pyelonephritis II: Diagnostic Studies and Management
Acute Kidney Injury III: Clinical Manifestations
Acute Kidney Injury II: Pathophysiology
Acute Kidney Injury I: Introduction
