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Updated: Jun 8, 2026

A 3D Organotypic Melanoma Spheroid Skin Model
Published on: May 18, 2018
Primary malignant melanoma of prostate.
M Doublali1, A Chouaib, A Khallouk
1Department of Urology, University Hospital Center Hassan II, Fez, Morocco.
Primary genitourinary melanoma is rare, often misattributed to the prostate but originating in the urethra. This case highlights the diagnostic challenges of this uncommon genitourinary malignancy.
Area of Science:
- Urologic Oncology
- Dermatology
- Pathology
Background:
- Primary genitourinary melanoma is exceedingly rare, comprising <1% of all melanoma cases.
- Most reported prostatic melanomas actually arise from the prostatic urethra.
Observation:
- This report details a case of primary malignant melanoma of the prostate.
- The diagnosis was incidentally made during a transurethral resection of the prostate (TURP).
Findings:
- Confirms the rarity of primary prostatic melanoma.
- Highlights the importance of considering urethral origin for suspected prostatic melanoma.
Implications:
- Underscores the diagnostic and management difficulties posed by rare genitourinary malignancies.
- Suggests vigilance for melanoma in prostatic tissues, especially during TURP procedures.
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