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Updated: Jun 8, 2026

A Microwave-Assisted Direct Heteroarylation of Ketones Using Transition Metal Catalysis
Published on: February 16, 2020
Decarboxylative homocoupling of (hetero)aromatic carboxylic acids
Josep Cornella1, Hicham Lahlali, Igor Larrosa
1Queen Mary University of London, School of Biological and Chemical Sciences, Joseph Priestley Building, Mile End Road, E1 4NS, London, UK.
Abstract:
A variety of hetero(aromatic) carboxylic acids are shown to undergo decarboxylative homocoupling, mediated by a Pd/Ag system. This novel methodology for the synthesis of symmetrical biaryls avoids the use of haloarenes and organometallic compounds as starting materials.
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