[Comparative therapeutic investigations of pivmecillinam and amoxycillin (author's transl)]

The therapeutic value of pivmecillinam and amoxycillin in urinary tract infections was compared in a double blind study. No therapeutic superiority or inferiority of either substance could be demonstrated. The study shows that a therapeutic comparison of two antibiotics using everyday treatment is possible. Before the introduction of new antibiotics at least equal effectiveness of the substance should be documented with appropriate investigations.