Related Experiment Video
Updated: Jun 8, 2026

08:09
Tubal Cytology of the Fallopian Tube as a Promising Tool for Ovarian Cancer Early Detection
Published on: July 25, 2017
Synchronous primary endometrial and fallopian tube cancers
E Terzakis1, G Androutsopoulos, C Grigoriadis
12nd Department of Gynecology, St. Savvas Anticancer-Oncologic Hospital, Athens, Greece.
European Journal of Gynaecological Oncology
|October 2, 2010
Summary
Synchronous primary endometrial and fallopian tube cancers are rare. This case highlights successful treatment and long-term remission, suggesting earlier detection may improve survival outcomes for these uncommon dual malignancies.
Area of Science:
- Gynecologic Oncology
- Pathology
- Clinical Medicine
Background:
- Synchronous primary cancers, occurring simultaneously, are infrequent in the general population.
- This report details a rare instance of concurrent primary endometrial and fallopian tube cancers.
Observation:
- A 54-year-old postmenopausal woman presented with abnormal vaginal bleeding.
- Surgical pathology confirmed independent primary endometrial and right fallopian tube malignancies.
- The patient received adjuvant chemotherapy and radiotherapy post-surgery.
Findings:
- The patient achieved a disease-free status 65 months post-treatment.
- The study reviews literature on synchronous endometrial and fallopian tube cancers.
- Survival rates for these synchronous cancers warrant further investigation.
Implications:
- Early detection and prompt treatment are crucial for managing synchronous gynecologic cancers.
- Understanding the biological and clinical factors influencing survival in these cases is essential.
- This case contributes to the limited literature on synchronous primary endometrial and fallopian tube cancers.
Related Concept Videos
Uterine Tubes
The uterine or fallopian tubes function as the conduit through which oocytes travel from the ovaries to the uterus. Each fallopian tube measures approximately 10 to 13 cm long and is anatomically divided into the infundibulum, ampulla, isthmus, and interstitial part (or intramural segment). The infundibulum is characterized by its funnel shape and features extensions called fimbriae which reach towards the peritoneal cavity. These fimbriae play a critical role during ovulation as they extend...
Disorders of the Female Reproductive System
The female reproductive system can be affected by several disorders, including Premenstrual Syndrome (PMS), Premenstrual Dysphoric Disorder (PMDD), endometriosis, and various forms of cancer. PMS and PMDD are cyclical conditions that cause physical and emotional distress, with symptoms that include edema, mood swings, and food cravings. PMDD is a more severe form of PMS characterized by increased symptom severity that peaks during the luteal phase and tends to improve or resolve shortly after...
Metastasis
Metastasis is the spread of cancer cells from the original site to distant locations in the body. Cancer cells can spread via blood vessels (hematogenous) as well as lymph vessels in the body.
Epithelial-to-Mesenchymal Transition
The epithelial-to-mesenchymal transition or EMT is a developmental process commonly observed in wound healing, embryogenesis, and cancer metastasis. EMT is induced by transforming growth factor-beta (TGF-β) or receptor tyrosine kinase (RTK) ligands, which further...
Epithelial-to-Mesenchymal Transition
The epithelial-to-mesenchymal transition or EMT is a developmental process commonly observed in wound healing, embryogenesis, and cancer metastasis. EMT is induced by transforming growth factor-beta (TGF-β) or receptor tyrosine kinase (RTK) ligands, which further...
Ovarian Cycle
The menstrual cycle includes a critical component known as the ovarian cycle, which undergoes two main phases each month—the follicular phase and the luteal phase. The follicular phase is variable and averaging around 14 days. Ovulation, triggered by a surge in luteinizing hormone (LH), marks the transition between the two phases. The second phase, the luteal phase, is relatively consistent, lasting approximately 14 days, and is marked by the activity of the corpus luteum. While a cycle length...
Uterus and Cervix
The uterus, commonly called the womb, is a vital reproductive organ in females designed to provide a nurturing environment for the implantation and growth of an embryo. It is shaped like a hollow pear and positioned between the urinary bladder and the rectum. The uterus's structure allows it to support and protect a developing fetus throughout pregnancy.
The uterus is securely anchored within the pelvic cavity by paired broad ligaments on either side. It is further stabilized by three pairs of...
The uterus is securely anchored within the pelvic cavity by paired broad ligaments on either side. It is further stabilized by three pairs of...

