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Related Concept Videos

Gastrointestinal Motility Disorders01:20

Gastrointestinal Motility Disorders

Gastrointestinal or GI motility disorders are characterized by irregular gastrointestinal tract movements, disrupting food transit from the mouth to the anus. They are caused by damage or dysfunction in gut muscles or nerves. These disorders can cause symptoms such as severe constipation, diarrhea, abdominal pain, and swallowing difficulties. Disorders can affect any segment of the GI tract and range widely in severity, from common conditions like GERD to life-threatening conditions like...
Inflammatory Bowel Disease III: Crohn's Disease01:25

Inflammatory Bowel Disease III: Crohn's Disease

Crohn’s disease is a chronic, relapsing form of inflammatory bowel disease characterized by segmental, transmural inflammation that can affect any part of the gastrointestinal tract. Its pathogenesis arises from a combination of genetic susceptibility, environmental exposures, epithelial barrier dysfunction, and immune dysregulation. Together, these factors lead to an exaggerated immune response against components of the gut microbiome.Genetic and Environmental InfluencesMultiple genetic...
Inflammatory Bowel Disease II: Crohn's Disease01:30

Inflammatory Bowel Disease II: Crohn's Disease

Introduction
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by transmural...
Chronic Bowel Disorders: Introduction01:17

Chronic Bowel Disorders: Introduction

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Inflammatory Bowel Disease I: Introduction01:26

Inflammatory Bowel Disease I: Introduction

Inflammatory bowel disease is a group of chronic disorders marked by recurrent inflammation of the gastrointestinal tract due to an abnormal immune response against gut microflora. This leads to tissue damage. The two main forms are Crohn’s disease and ulcerative colitis.Crohn’s DiseaseCrohn’s disease is a relapsing inflammatory disorder that can affect any part of the GI tract, from the mouth to the anus. It involves all layers of the bowel wall (transmural) and shows “skip lesions” in which...
Intestinal Obstruction I: Introduction01:29

Intestinal Obstruction I: Introduction

Intestinal obstruction is a partial or complete blockage of the small or large intestine that disrupts the normal flow of intestinal contents through the lumen. This interruption impairs digestion, absorption, and fluid balance, and may lead to serious complications if not treated promptly.Mechanical ObstructionMechanical obstruction occurs when a physical blockage prevents intestinal contents from passing, arising from within the lumen or the bowel wall, or from external compression.Adhesions,...

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Related Experiment Videos

Gastrointestinal carcinoid tumors.

M J Varas-Lorenzo1, F Muñoz-Agel, J C Espinós-Pérez

  • 1Unit of Endoscopy, Centro Médico Teknon, Barcelona, Spain. varas@dr.teknon.es

Revista Espanola De Enfermedades Digestivas
|October 2, 2010
PubMed
Summary

This study reviewed gastrointestinal carcinoid tumors (CTs) in 40 patients over 16 years. Earlier diagnosis and endoscopic treatment led to lower carcinoid syndrome rates and higher survival.

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Area of Science:

  • Gastroenterology
  • Oncology
  • Endocrinology

Background:

  • Carcinoid tumors (CTs) are the most common neuroendocrine tumors.
  • Gastrointestinal CTs are typically diagnosed via surgical specimens, clinical evaluation, and imaging.
  • Diagnosis relies on endoscopy, echoendoscopy, CT scans, and Octreoscan.

Purpose of the Study:

  • To review a personal series of gastrointestinal carcinoid tumors.
  • To compare findings with existing literature on CTs.
  • To analyze trends in diagnosis, treatment, and outcomes.

Main Methods:

  • Retrospective review of 40 Caucasian patients with over 50 gastrointestinal carcinoid tumors.
  • Data collected over a 16-year period (1994-2009).
  • Inclusion of multiple tumor cases per patient.

Main Results:

  • Mean patient age was 52 years, with 50% females.
  • Gastroduodenal (42.5%) and rectal (30%) tumors were most common, often treated endoscopically.
  • Low rates of metastasis (5%) and carcinoid syndrome (CS) (5%), with an 85% survival rate.

Conclusions:

  • Patient demographics align with literature findings.
  • Increased detection of gastroduodenal and rectal CTs may be due to endoscopic bias.
  • Lower CS rates and higher survival suggest earlier diagnosis and treatment are effective.