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Updated: Jun 8, 2026

A Cost-effective and Reliable Method to Predict Mechanical Stress in Single-use and Standard Pumps
Published on: August 5, 2015
Prediction of leakage flow in a shrouded centrifugal blood pump
Ji-Bin Teo1, Weng-Kong Chan, Yew-Wah Wong
1School of Mechanical and Aerospace Engineering, Nanyang Technological University, Singapore.
Abstract:
This article proposes a phenomenological model to predict the leakage flow in the clearance gap of shrouded centrifugal blood pumps. A good washout in the gap clearance between the rotating impeller surfaces and volute casing is essential to avoid thrombosis. However, excessive leakage flow will result in higher fluid shear stress that may lead to hemolysis. Computational fluid dynamics (CFD) analysis was performed to investigate the leakage flow in a miniaturized shrouded centrifugal blood pump operating at a speed of 2000 rpm. Based on an analytical model derived earlier, a phenomenological model is proposed to predict the leakage flow. The leakage flow rate is found to be proportional to h(α) , where h is the gap size and the exponent α ranges from 2.955 to 3.15 for corresponding gap sizes of 0.2-0.5 mm. In addition, it is observed that α is a linear function of the gap size h. The exponent α compensates for the variation of pressure difference along the circumferential direction as well as inertia effects that are dominant for larger gap clearances. The proposed model displays good agreement with computational results. The CFD analysis also showed that for larger gap sizes, the total leakage flow rate is of the same order of magnitude as the operating flow rate, thus suggesting low volumetric efficiency.
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