Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Cardiopulmonary Resuscitation V: Advanced Airway Management Techniques01:30

Cardiopulmonary Resuscitation V: Advanced Airway Management Techniques

Airway management is essential in emergency and surgical medicine, ensuring ventilation and oxygenation in patients who cannot maintain their own airway. Clinicians use a range of techniques and devices to secure the airway, depending on the patient’s condition and the clinical context. Key methods include endotracheal intubation, rapid sequence intubation (RSI), supraglottic airway devices, and advanced visualization aids. In cases where these approaches fail, surgical airway interventions are...
Tracheostomy Decannulation01:21

Tracheostomy Decannulation

Tracheostomy decannulation is a significant milestone in the liberation of mechanically ventilated patients. Despite its importance, there is no universally accepted protocol for this procedure. This demands an evidence-based, individualized approach.
Description of the Procedure
Decannulation refers to the permanent removal of the tracheostomy tube, signaling the resolution of the condition that initially necessitated the tracheostomy. The process requires a well-coordinated interplay between...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Layer-Specific Retinal Perfusion as a Personalized Biomarker: Evaluating the Subclinical Microanatomical Effects of Intracameral Cefuroxime After Routine Cataract Surgery.

Journal of personalized medicine·2026
Same author

Midterm outcome of supra-aortic vessels reconstruction: A single-center report.

JTCVS structural and endovascular·2026
Same author

The impact of modified esophageal stenting on oral intake in delayed spontaneous esophageal perforation.

Journal of cardiothoracic surgery·2026
Same author

Operative and hemostatic differences between acute type A intramural hematoma and aortic dissection.

Surgery·2026
Same author

From Supplements to Sight: Quantifying the Impact of Lutein and Carotenoid on Age-Related Macular Degeneration-A Systematic Review and Meta-Analysis of Randomized Controlled Trials.

Journal of ophthalmology·2026
Same author

The effects of neoadjuvant chemoradiotherapy-related frailty by analytic morphomics in esophageal cancer.

Journal of cardiothoracic surgery·2026

Related Experiment Video

Updated: Jun 8, 2026

Design of a Biocompatible Drug-Eluting Tracheal Stent in Mice with Laryngotracheal Stenosis
08:26

Design of a Biocompatible Drug-Eluting Tracheal Stent in Mice with Laryngotracheal Stenosis

Published on: January 21, 2020

Experimental absorbable stent permits airway remodeling.

Kuo-Sheng Liu1, Yun-Hen Liu, Yi-Jie Peng

  • 1Department of Mechanical Engineering, Chang Gung University, and Department of Thoracic and Cardiovascular Surgery, Chang Gung Memorial Hospital, Kwei-Shan, Tao-Yuan, Taiwan.

The Journal of Thoracic and Cardiovascular Surgery
|October 2, 2010
PubMed
Summary

A new polycaprolactone (PCL) stent shows promise for airway remodeling, demonstrating good safety and biocompatibility in rabbit trachea studies. This bioresorbable stent offers potential advantages over traditional metallic and silicone options.

More Related Videos

Fabrication of Small Caliber Stent-grafts Using Electrospinning and Balloon Expandable Bare Metal Stents
06:55

Fabrication of Small Caliber Stent-grafts Using Electrospinning and Balloon Expandable Bare Metal Stents

Published on: October 26, 2016

Related Experiment Videos

Last Updated: Jun 8, 2026

Design of a Biocompatible Drug-Eluting Tracheal Stent in Mice with Laryngotracheal Stenosis
08:26

Design of a Biocompatible Drug-Eluting Tracheal Stent in Mice with Laryngotracheal Stenosis

Published on: January 21, 2020

Fabrication of Small Caliber Stent-grafts Using Electrospinning and Balloon Expandable Bare Metal Stents
06:55

Fabrication of Small Caliber Stent-grafts Using Electrospinning and Balloon Expandable Bare Metal Stents

Published on: October 26, 2016

Area of Science:

  • Biomaterials Science
  • Regenerative Medicine
  • Surgical Innovation

Background:

  • Metallic and silicone stents are effective for airway lesions but have limitations.
  • Bioresorbable stents offer advantages by dissolving after tissue remodeling.
  • Developing novel bioresorbable materials is crucial for advanced medical devices.

Purpose of the Study:

  • To design and fabricate a novel mesh-type bioresorbable stent using polycaprolactone (PCL).
  • To evaluate the safety and biocompatibility of the PCL stent in a rabbit trachea model.
  • To assess the mechanical properties and degradation profile of the PCL stent.

Main Methods:

  • Fabrication of PCL stents using microinjection molding.
  • In vitro mechanical strength testing compared to silicone stents.
  • Surgical implantation of PCL stents into rabbit tracheas, followed by regular bronchoscopic and histological examinations.

Main Results:

  • No animal mortality; minor complications included distal stent migration (1 rabbit) and secretion accumulation (2 rabbits).
  • Histological analysis revealed intact ciliated epithelium and leukocyte infiltration, indicating biocompatibility.
  • The PCL stent exhibited minimal degradation and preserved mechanical strength over 33 weeks.

Conclusions:

  • The PCL stent demonstrated good safety and biocompatibility for airway remodeling applications.
  • Polycaprolactone (PCL) is a promising material for bioresorbable stent design, especially when extended degradation is needed.