Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Skin Diseases and Disorders

Skin Diseases and Disorders

Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...

Staphylococcal Skin Infections

Staphylococcal Skin Infections

Staphylococcus aureus is a Gram-positive coccus that resides harmlessly on the skin and mucous membranes of healthy individuals. When the skin barrier is breached, it can shift from a commensal to an opportunistic pathogen. This transition is facilitated by surface adhesins, such as clumping factor B and S. aureus surface protein G (SasG), which bind to structural proteins, including loricrin and cytokeratin, in the damaged epidermis. Protein A, another key factor, binds the Fc region of...

Immunodeficiency Diseases

Immunodeficiency Diseases

Immunodeficiency disorders are conditions in which the immune system's ability to fight infectious disease and cancer is compromised or entirely absent. The immune system comprises a complex network of cells, tissues, and organs that work together to protect the body from potentially harmful invaders. When this system is deficient or not functioning properly, it leaves the body susceptible to infections, diseases, or other complications.
There are three main causes of immunodeficiency disorders...

Leishmaniasis

Leishmaniasis

Leishmaniasis is a protozoal disease caused by species of the genus Leishmania and transmitted through the bite of infected female sandflies. The parasite exists in two principal morphological forms during its life cycle. A sandfly acquires intracellular amastigotes from an infected reservoir host, such as a dog. Within the sandfly, these forms differentiate into motile, flagellated promastigotes. During a subsequent blood meal, promastigotes are injected into the human host, where they...

Endocarditis II: Clinical Features of Infective Endocarditis

Endocarditis II: Clinical Features of Infective Endocarditis

Endocarditis can present various clinical features depending on the causative organism and the patient's underlying health conditions. Initially, the clinical features of infective endocarditis develop gradually, presenting with nonspecific symptoms that can be easily mistaken for other illnesses.General SymptomsEarly symptoms of infective endocarditis are fever, chills, weakness, malaise, fatigue, and weight loss. These symptoms reflect the systemic nature of the infection and the body's...

Papillary Dermis

Papillary Dermis

Dermis
The dermis might be considered the "core" of the integumentary system, as distinct from the epidermis and hypodermis. It contains blood and lymph vessels, nerves, and other structures, such as hair follicles and sweat glands. The dermis is made of two layers of connective tissue that comprise an interconnected mesh of elastin and collagenous fibers, produced by fibroblasts.
Papillary Layer
The papillary layer is made of loose, areolar connective tissue, which means the collagen and...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Exploring AI as a Diagnostic Tool in Medical Imaging for Dermatopathological Diseases.

Indian journal of dermatology·2026

Same author

Crystal Engineering and Self-Assembled Nanoring Formation with Purine-Cd<sup>II</sup>/Hg<sup>II</sup> Supramolecular Frameworks.

Chemistry, an Asian journal·2024

Same author

Identification of inhibitor against H. pylori HtrA protease using structure-based virtual screening and molecular dynamics simulations approaches.

Microbial pathogenesis·2018

Same author

Epidermolysis Bullosa Acquisita.

Indian journal of dermatology, venereology and leprology·2017

Same author

Reliability of specific finger dermatoglyphic patterns and their association with dental caries.

General dentistry·2014

Same author

Pharmacophore modelling and electronic feature analysis of hydroxamic acid derivatives, the HIV integrase inhibitors.

SAR and QSAR in environmental research·2013

Search research articles

Related Experiment Video

Updated: Jun 8, 2026

A Metadata Extraction Approach for Clinical Case Reports to Enable Advanced Understanding of Biomedical Concepts

A Metadata Extraction Approach for Clinical Case Reports to Enable Advanced Understanding of Biomedical Concepts

Published on: September 20, 2018

Post febrile acquired cutis laxa.

R Muthukumaran¹, G Nirmaladevi, G Sentamilselvi

¹Department of Dermatology, Chennai Medical College, Chennai-600 003, India.

Indian Journal of Dermatology, Venereology and Leprology

|October 2, 2010

Summary

A rare case of acquired cutis laxa occurred in the neck after enteric fever. Biopsy showed fragmented elastic fibers, highlighting this localized presentation following a febrile illness.

Related Experiment Videos

Last Updated: Jun 8, 2026

A Metadata Extraction Approach for Clinical Case Reports to Enable Advanced Understanding of Biomedical Concepts

A Metadata Extraction Approach for Clinical Case Reports to Enable Advanced Understanding of Biomedical Concepts

Published on: September 20, 2018

Area of Science:

Dermatology
Pathology
Infectious Diseases

Background:

Acquired cutis laxa is a rare connective tissue disorder characterized by loss of skin elasticity.
While typically generalized, localized forms can occur, often associated with underlying conditions.
Enteric fever, a systemic infection, is not commonly linked to dermatological manifestations like cutis laxa.

Purpose of the Study:

To report an unusual case of acquired cutis laxa localized to the neck region.
To investigate the histopathological findings in this specific presentation.
To contribute to the understanding of rare dermatological sequelae of febrile illnesses.

Main Methods:

Clinical case presentation of a male patient with acquired cutis laxa.
Dermato-histopathological examination of skin biopsy from the affected neck area.
Special staining techniques to visualize dermal elastic fibers.

Main Results:

The patient developed localized acquired cutis laxa following enteric fever.
Histopathology revealed fragmented elastic fibers within the dermis.
Special stains confirmed the degeneration and paucity of elastic tissue.

Conclusions:

Acquired cutis laxa can present in a localized form following systemic febrile illness, such as enteric fever.
Histopathological examination is crucial for diagnosing and understanding the underlying changes in elastic tissue.
This case underscores the importance of considering rare dermatological manifestations in the aftermath of infections.