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Updated: Jun 8, 2026
A Standardized Procedure of Dressing Management for Toxic Epidermal Necrolysis
Published on: March 14, 2025
Evaluation of chronic wound treatment with the SNaP wound care system versus modern dressing protocols
Bruce Lerman1, Leslie Oldenbrook, Shaundra L Eichstadt
1San Jose, Stanford, and Sunnyvale, Calif. From the O'Connor Wound Care Clinic, O'Connor Hospital; the Divisions of Plastic and Reconstructive Surgery and Vascular Surgery, Department of Surgery, Stanford University School of Medicine, Stanford University; and Spiracur, Inc.
Background:
Traditional negative-pressure wound therapy systems use an electrically powered pump to generate negative pressure at the wound bed. The SNaP Wound Care System is a novel, ultraportable device that delivers negative-pressure wound therapy without the use of an electrically powered pump.
Methods:
At an outpatient wound care clinic, 21 subjects with difficult-to-treat lower extremity ulcers received treatment with the SNaP System and were evaluated for wound healing for up to 4 months. Outcomes were then compared with 42 patient-matched controls treated at the same center with modern wound care protocols that included the use of Apligraf, Regranex, and skin grafting.
Results:
In the SNaP-treated group, 100 percent of subjects demonstrated improvement in wound size and 86 percent (18 of 21) exhibited a statistically significant healing trend (p < 0.05). Using Kaplan-Meier estimates of wound healing, SNaP-treated subjects healed in an average of 74.25 ± 20.1 days from the start of SNaP treatment and the matched controls healed in an average of 148.73 ± 63.1 days from the start of conventional treatment. This significantly faster healing time represents a 50 percent absolute reduction in time to healing (p < 0.0001) for subjects treated with the SNaP device.
Conclusions:
The findings reported here for the SNaP Wound Care System are similar to published reports for powered negative-pressure wound therapy devices for the treatment of highly challenging lower extremity wounds. This study suggests that the SNaP Wound Care System may be a useful addition to the techniques available to the wound care clinician.
