Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Esophageal Perforation-I: Introduction01:22

Esophageal Perforation-I: Introduction

Esophageal perforation is a severe medical condition characterized by a breach in the integrity of the esophageal wall. This breach can occur due to various factors such as trauma, medical procedures, or underlying diseases. When the esophageal wall is compromised, it allows food, fluids, and digestive juices into the chest cavity or adjacent structures, leading to potential complications and health risks.
The location of esophageal perforation can vary, occurring anywhere along the esophagus.
Inflammatory Bowel Disease I: Ulcerative Colitis01:27

Inflammatory Bowel Disease I: Ulcerative Colitis

Introduction
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
Flail Chest-I01:24

Flail Chest-I

Overview of Flail Chest
Flail chest is a severe and potentially life-threatening condition characterized by the fracture of three or more adjacent ribs in multiple places. It is most commonly caused by direct impacts and trauma, such as motor vehicle accidents or injuries from a steering wheel impact. It can also occur due to falls in elderly individuals with osteoporosis, or assaults involving sharp objects.
Pathophysiology
The pathophysiology of flail chest is complex, involving fractures of...
Acute Pancreatitis I: Introduction01:25

Acute Pancreatitis I: Introduction

Acute pancreatitis is the sudden inflammation of the pancreas caused by the early activation of digestive enzymes, leading to the autodigestion of pancreatic tissue. This results in local inflammation and, in severe cases, systemic complications.EtiologyUnderstanding the underlying causes is crucial, as identifying the etiology guides treatment and anticipates complications. Acute pancreatitis can be triggered by various factors, typically grouped into the following clinical categories.Biliary...
Flail Chest-II01:26

Flail Chest-II

Managing flail chest, a condition characterized by a segment of the chest wall moving independently from the rest of the thoracic cage, requires a comprehensive approach. It includes a thorough assessment of the patient's condition, a diagnostic evaluation to determine the extent of the injury, and the implementation of appropriate medical interventions tailored to the individual's needs.
Assessment:
1. Clinical Evaluation:
History:
Hemorrhagic Stroke ll: Pathophysiology01:29

Hemorrhagic Stroke ll: Pathophysiology

A hemorrhagic stroke develops when a cerebral blood vessel ruptures, allowing blood to escape into the surrounding brain tissue, as in intracerebral hemorrhage (ICH), or into the subarachnoid space, as in subarachnoid hemorrhage (SAH). Because the skull is a rigid compartment, the sudden presence of extravascular blood rapidly increases intracranial pressure and compresses adjacent neural structures, leading to immediate tissue injury and impaired cerebral perfusion.Mass Effect and Primary...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Best Case/Worst Case-ICU: protocol for a multisite, stepped-wedge, randomised clinical trial of scenario planning to improve communication in the ICU in US trauma centres for older adults with serious injury.

BMJ open·2024
Same author

Letter to the editor: Routine screening bronchoscopy in intubated trauma patients risks unnecessary antibiotic use without clear clinical benefit.

The journal of trauma and acute care surgery·2023
Same author

Effect of Delay and Disruption in Venous Thromboembolism Prophylaxis in Trauma Patients: Case-Control Study.

Journal of the American College of Surgeons·2022
Same author

Making your geriatric and palliative programs a strength: TQIP guideline implementation and the VRC perspective.

Trauma surgery & acute care open·2021
Same author

Effect of Flumazenil on Hypoactive Delirium in the ICU: A Double-Blind, Placebo-Controlled Pilot Study.

Critical care explorations·2020
Same author

Trauma and acute care surgeons report prescribing less opioids over time.

Trauma surgery & acute care open·2019
Same journal

How to establish and run a national ICU benchmarking registry.

Current opinion in critical care·2026
Same journal

Cardiogenic shock - toward phenotype-directed, precision management.

Current opinion in critical care·2026
Same journal

The future of critical care nutrition: from calorie counting to precision personalized metabolism therapy.

Current opinion in critical care·2026
Same journal

Editorial introduction.

Current opinion in critical care·2026
Same journal

Generative artificial intelligence for outcome prediction in critical care: the future is now?

Current opinion in critical care·2026
Same journal

Feeding under support in critical care illness: metabolic and nutritional management during extracorporeal membrane oxygenation and continuous renal replacement therapy.

Current opinion in critical care·2026
See all related articles

Related Experiment Video

Updated: Jun 8, 2026

Application of Laparoscopic Partial Splenectomy with Total Blood Flow Occlusion in Benign Splenic Lesions
02:09

Application of Laparoscopic Partial Splenectomy with Total Blood Flow Occlusion in Benign Splenic Lesions

Published on: December 20, 2024

Blunt splenic injury.

Christine S Cocanour1

  • 1University of California Davis Medical Center, Sacramento, California 95817, USA. Christine.cocanour@ucdmc.ucdavis.edu

Current Opinion in Critical Care
|October 2, 2010
PubMed
Summary
This summary is machine-generated.

Nonoperative management (NOM) is standard for stable patients with blunt splenic injury. Angioembolization enhances splenic salvage, even for high-grade injuries, allowing early discharge and minimizing complications.

Related Experiment Videos

Last Updated: Jun 8, 2026

Application of Laparoscopic Partial Splenectomy with Total Blood Flow Occlusion in Benign Splenic Lesions
02:09

Application of Laparoscopic Partial Splenectomy with Total Blood Flow Occlusion in Benign Splenic Lesions

Published on: December 20, 2024

Area of Science:

  • Trauma Surgery
  • Emergency Medicine
  • Surgical Critical Care

Background:

  • Blunt splenic trauma is a common cause of intra-abdominal injury.
  • Management decisions are guided by hemodynamic stability and injury grade.
  • Traditional management often involved splenectomy, but nonoperative approaches are evolving.

Purpose of the Study:

  • To review current management strategies for patients with splenic injuries.
  • To highlight the role of nonoperative management (NOM) and splenic salvage.
  • To discuss the impact of angioembolization on outcomes.

Main Methods:

  • Review of current literature and clinical practice guidelines.
  • Analysis of outcomes based on injury grade and management strategy (operative vs. nonoperative).
  • Evaluation of the effectiveness and safety of angioembolization.

Main Results:

  • Up to 38% of splenic injuries can be successfully managed nonoperatively.
  • Angioembolization significantly increases splenic salvage rates with minimal complications.
  • Patients with low-grade injuries are discharged in 1-2 days; high-grade injuries in 3-4 days.
  • Delayed hemorrhage is a concern, but readmission rates for splenectomy are low.

Conclusions:

  • Nonoperative management (NOM) is the standard of care for hemodynamically stable patients with isolated blunt splenic injury.
  • Angioembolization improves splenic salvage, even for higher-grade injuries.
  • Careful patient selection, monitoring, and follow-up are crucial for safe NOM.