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Membranoproliferative glomerulonephritis in a fifteen-month-old boy
S James1, R Neiberger, W Donnelly
1Department of Pediatrics, College of Medicine, University of Florida, Gainesville.
Insights
Membranoproliferative glomerulonephritis (MPGN) was diagnosed in a 15-month-old boy presenting with severe kidney symptoms. This case highlights that MPGN can manifest in early childhood, challenging typical age-related assumptions.
Area of Science:
- Pediatric Nephrology
- Renal Pathology
- Glomerular Diseases
Background:
- Membranoproliferative glomerulonephritis (MPGN) is a rare kidney disease.
- MPGN is typically diagnosed in older children and young adults.
- Early-onset MPGN is infrequently reported.
Abstract:
A 15-month-old boy presented with hypertension, edema, heavy proteinuria, gross hematuria and renal insufficiency. A renal biopsy was consistent with classical membranoproliferative glomerulonephritis type I. Although usually thought of as a disease in older children and young adults, membranoproliferative glomerulonephritis can occur as early as the second year of life.