Passive smoking and the development of cardiovascular disease in children: a systematic review

Giorgos S Metsios1, Andreas D Flouris, Manuela Angioi

  • 1School of Sport, Performing Arts and Leisure, University of Wolverhampton, Walsall, West Midlands WS1 3BD, UK.

Insights

Secondhand smoke exposure in children is linked to factors that can lead to cardiovascular disease (CVD). This systematic review found it may negatively impact cholesterol levels and blood vessel function in kids.

Area of Science:

  • Pediatric Health
  • Environmental Health
  • Cardiovascular Disease Research

Background:

  • Children's developing physiological systems may be particularly vulnerable to environmental toxins.
  • Passive smoking (secondhand smoke exposure) is a recognized public health concern.
  • Existing research suggests potential links between passive smoking and adverse health outcomes in children.

Purpose of the Study:

  • To systematically investigate the association between passive smoking and factors influencing cardiovascular disease (CVD) development in children.
  • To synthesize evidence on how secondhand smoke affects pediatric cardiovascular health indicators.
  • To identify specific cardiovascular risk factors potentially exacerbated by passive smoking in pediatric populations.

Main Methods:

  • Systematic literature search across multiple databases including Medline, Cochrane Library, CINAHL, Google Scholar, and EMBASE.
  • Inclusion of relevant articles from major governmental reports (Surgeon General's report, California EPA report).
  • Analysis of 42 identified articles, comprising 30 reviews and 12 observational studies.

Main Results:

  • Passive smoking is associated with unfavorable high-density lipoprotein (HDL) cholesterol levels in children.
  • Evidence suggests passive smoking contributes to deteriorated vascular function in pediatric populations.
  • The findings indicate a potential link between secondhand smoke exposure and early cardiovascular risk factors in children.

Conclusions:

  • Passive smoking exposure may negatively impact key indicators of cardiovascular health in children.
  • Deterioration in HDL levels and vascular function are potential consequences of secondhand smoke exposure in youth.
  • Further research and public health interventions are warranted to mitigate the cardiovascular risks of passive smoking in children.

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