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Related Concept Videos

Pleiotropy01:33

Pleiotropy

Pleiotropy is the phenomenon in which a single gene impacts multiple, seemingly unrelated phenotypic traits. For example, defects in the SOX10 gene cause Waardenburg Syndrome Type 4, or WS4, which can cause defects in pigmentation, hearing impairments, and an absence of intestinal contractions necessary for elimination. This diversity of phenotypes results from the expression pattern of SOX10 in early embryonic and fetal development. SOX10 is found in neural crest cells that form melanocytes,...
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Oogenesis,  the process of developing egg cells (female gametes), occurs within the ovaries and is fundamental to female fertility. This sequence begins during fetal development when diploid oogonia in the developing ovaries undergo mitotic divisions to produce primary oocytes. By birth, these primary oocytes enter prophase I of meiosis but become arrested in this stage, remaining suspended until puberty.
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Polytene chromosomes are giant interphase chromosomes with several DNA strands placed side by side. They were discovered in the year 1881 by Balbiani in salivary glands, intestine, muscles, malpighian tubules, and hypoderm of larvae Chironomus plumosus. Hence, these are also called "Salivary gland chromosomes." These are found in insects of the order Diptera and Collembola; in certain organs of mammals; and synergids, antipodes of flowering plants. Polytene chromosomes are also regularly...
Polytene Chromosomes02:04

Polytene Chromosomes

Polytene chromosomes are giant interphase chromosomes with several DNA strands placed side by side. They were discovered in the year 1881 by Balbiani in salivary glands, intestine, muscles, malpighian tubules, and hypoderm of larvae Chironomus plumosus. Hence, these are also called "Salivary gland chromosomes." These are found in insects of the order Diptera and Collembola; in certain organs of mammals; and synergids, antipodes of flowering plants. Polytene chromosomes are also regularly...
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Updated: Jun 8, 2026

Anterior High-Resolution Optical Coherence Tomography in the Diagnosis and Therapeutic Monitoring of Ocular Surface Squamous Neoplasia
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Anterior High-Resolution Optical Coherence Tomography in the Diagnosis and Therapeutic Monitoring of Ocular Surface Squamous Neoplasia

Published on: August 9, 2024

Osteopoikilosis.

P Ellanti1, B Clarke, J Gray

  • 1Department of Emergency Medicine, Adelaide and Meath incorporating National Childrens Hospital, Tallaght, Dublin 24, Ireland. prasad.ellanti@gmail.com

Irish Journal of Medical Science
|October 2, 2010
PubMed
Summary
This summary is machine-generated.

Osteopoikilosis is a rare, asymptomatic bone disease characterized by dense lesions on X-rays. This benign condition, osteopoikilosis, requires no specific treatment and is often found incidentally.

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Area of Science:

  • Skeletal Dysplasias
  • Radiology
  • Bone Diseases

Background:

  • Osteopoikilosis is a rare, asymptomatic skeletal disorder.
  • It is characterized by multiple, small, dense bone lesions.
  • Radiographically, these lesions can be mistaken for metastatic disease.

Observation:

  • A case of osteopoikilosis was incidentally diagnosed in a 24-year-old female patient.
  • The diagnosis was based on radiographic findings of multiple, small, circular or oval shaped radio-dense lesions.
  • The patient presented with no symptoms related to the bone condition.

Findings:

  • Osteopoikilosis presents as multiple, small, circular or oval, radio-dense lesions on plain radiographs.
  • These radiographic findings are diagnostic of osteopoikilosis.
  • The condition is a benign sclerosing dysplasia of bone.

Implications:

  • Osteopoikilosis is a benign condition requiring no specific treatment.
  • Incidental radiographic findings of osteopoikilosis necessitate accurate diagnosis to avoid misinterpretation as metastatic disease.
  • Understanding the radiographic presentation is crucial for correct clinical management.