Mucosal healing in inflammatory bowel disease: where do we stand?
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Updated: Jun 8, 2026

Performing Colonoscopic-Guided Pinch Biopsies in Mice and Evaluating Subsequent Tissue Changes
Published on: February 5, 2021
Christina Ha1, Asher Kornbluth
1Division of Gastroenterology and Hepatology, The Johns Hopkins School of Medicine, Baltimore, MD 21287, USA. christina.ha@jhmi.edu
Abstract:
The definition of remission in Crohn's disease and ulcerative colitis has evolved to include mucosal healing as a measure of treatment efficacy. Randomized, controlled trials have demonstrated mucosal healing is attainable with the current arsenal of therapies available to treat inflammatory bowel disease. Mucosal healing has been shown to reduce the likelihood of clinical relapse, reduce the risk of future surgeries, and reduce hospitalizations. This review focuses on the latest studies addressing clinical outcomes of mucosal healing in the clinical trial and practice setting.
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