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Monitoring Lung Function with Electrical Impedance Tomography in the Intensive Care Unit

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Indium lung--case reports and epidemiology.

Kazuyuki Omae¹, Makiko Nakano, Akiyo Tanaka

¹Department of Preventive Medicine and Public Health, School of Medicine, Keio University, 35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan. omae@sc.itc.keio.ac.jp

International Archives of Occupational and Environmental Health

|October 2, 2010

Summary

Indium Lung is a new occupational lung disease caused by exposure to indium compounds. Early detection and monitoring are crucial for preventing lung damage in exposed workers.

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Last Updated: Jun 8, 2026

Monitoring Lung Function with Electrical Impedance Tomography in the Intensive Care Unit

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Published on: September 6, 2024

Area of Science:

Occupational Medicine
Pulmonology
Toxicology

Background:

Indium compounds are used in various industrial applications.
Exposure to indium can lead to significant lung damage.
Indium Lung is an emerging occupational lung disease.

Observation:

Review of case reports and epidemiological studies on indium-related lung diseases.
Identified cases of interstitial pneumonia and pulmonary alveolar proteinosis (PAP) in indium-exposed workers.
Cross-sectional surveys in Japan indicated lung damage from indium exposure.

Findings:

Hardly soluble indium compounds cause interstitial and emphysematous lung damages, termed "Indium Lung".
Japan Society for Occupational Health proposed a biological exposure limit for indium in serum (3 μg/l) based on KL-6 levels.
Clinical manifestations may differ between Japanese and US cases.

Implications:

Long-term follow-up of indium-exposed workers is essential for understanding disease progression and lung cancer incidence.
Further research is needed to elucidate the mechanism of Indium Lung.
Establishing occupational exposure limits and monitoring strategies is critical for worker protection.