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Anterior uveitis associated with high-dose cytosine arabinoside
Robert E Fintelmann1, Ying Qian, Alison Skalet
1The Francis I. Proctor Foundation and Department of Ophthalmology, University of California-San Francisco, San Francisco, California 4143-0730, USA.
Purpose:
To report a case of anterior uveitis associated with high-dose cytosine arabinoside (Ara-C) treatment.
Design:
Observational case report.
Methods:
A 14-year-old girl was seen for pain, redness, and photophobia shortly after finishing a cycle of high-dose Ara-C.
Results:
Portable slit-lamp examination revealed bilateral diffuse fine keratic precipitates, indicative of a nongranulomatous anterior uveitis. This was treated successfully with a course of topical prednisolone acetate 1%.
Conclusions:
Ophthalmologists who are asked to evaluate patients on high-dose Ara-C for a "red eye" should consider anterior uveitis as a potential diagnosis.
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