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Related Experiment Video

Updated: Jun 8, 2026

Detecting Abnormalities in Choroidal Vasculature in a Mouse Model of Age-related Macular Degeneration by Time-course Indocyanine Green Angiography

Detecting Abnormalities in Choroidal Vasculature in a Mouse Model of Age-related Macular Degeneration by Time-course Indocyanine Green Angiography

Published on: February 19, 2014

Polypoidal choroidal vasculopathy: recent advances in therapy.

G de Crecchio¹, R V P Chan, G Manzi

¹Dipartimento di Oftalmologia, Università degli Studi di Napoli "Federico II", Naples, Italy.

Current Drug Targets

|October 5, 2010

Summary

Polypoidal Choroidal Vasculopathy (PCV) causes recurrent retinal detachments and can mimic age-related macular degeneration (AMD). This review discusses PCV and combination therapy treatments.

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In Vivo Multimodal Imaging and Analysis of Mouse Laser-Induced Choroidal Neovascularization Model

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Published on: January 21, 2018

Area of Science:

Ophthalmology
Retinal Diseases
Choroidal Vasculopathy

Background:

Polypoidal Choroidal Vasculopathy (PCV) is a condition causing chronic, recurrent serous and/or hemorrhagic detachments of the retinal pigment epithelium (RPE) and neurosensory retina.
While often associated with Asian and pigmented populations, PCV can also affect Caucasian patients presenting with clinical features similar to age-related macular degeneration (AMD).

Purpose of the Study:

To discuss Polypoidal Choroidal Vasculopathy (PCV).
To review current and emerging treatment strategies for PCV.
To highlight the role of combination therapy in managing PCV.

Main Methods:

Literature review of studies on PCV.
Analysis of clinical presentations and diagnostic criteria for PCV.
Evaluation of treatment outcomes for various therapeutic approaches, including combination therapy.

Main Results:

PCV is characterized by specific vascular abnormalities under the retina.
Early diagnosis and treatment are crucial for managing PCV and preventing vision loss.
Combination therapy may offer improved outcomes for certain PCV patients.

Conclusions:

PCV requires careful diagnosis, distinguishing it from typical AMD.
Treatment strategies for PCV are evolving, with combination therapy showing promise.
Further research is needed to optimize PCV management and long-term visual outcomes.