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Updated: Jun 8, 2026

In vitro Assessment of Myocardial Protection following Hypothermia-Preconditioning in a Human Cardiac Myocytes Model
Published on: October 27, 2020
Induced hypothermia prior to left ventricular assist device
Mark A Thompson1, Mohi Alkadri, Paul McMullan
1Ochsner Heart and Vascular Institute, 1514 Jefferson Highway, New Orleans, LA 70121, USA. mathompson@ochsner.org
Abstract:
Induced hypothermia, a therapy that recently gained the attention of a broad spectrum of US and international medical authorities for its neuroprotective benefits in post-cardiac arrest patients, may represent an underexplored therapeutic option in patients with severe cardiac failure by optimizing hemodynamics and augmenting cardiac contractility. The authors present the first case report, to their knowledge, of a patient with severe congestive heart failure who underwent cooling prior to successful left ventricular assist device implantation.
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