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Related Concept Videos

Stem Cell Therapy for Tissue Regeneration01:21

Stem Cell Therapy for Tissue Regeneration

Stem cell therapy is a method used in regenerative medicine to repair and restore function to damaged tissues and organs. Stem cells have the potential to proliferate and differentiate into various tissue types, making them ideal candidates for tissue regeneration. For example, hematopoietic stem cell transplants are commonly used in blood cancer treatment to replenish damaged bone marrow and restore healthy blood cells.
Types of Stem Cells used in Stem Cell Therapy
The two main cell types that...
Stem Cell Culture01:17

Stem Cell Culture

Stem cell research aims to find ways to use stem cells to regenerate and repair cellular damage. Over time, most adult cells undergo the wear and tear of aging and lose their ability to divide and repair themselves. Stem cells do not display a particular morphology or function. Adult stem cells, which exist as a small subset of cells in most tissues, keep dividing and can differentiate into a number of specialized cells generally formed by that tissue. These cells enable the body to renew and...
Source And Potency Of Stem Cells01:27

Source And Potency Of Stem Cells

Stem cells are undifferentiated cells with extensive self-renewal properties that help them maintain their population during the fetal and adult stages of life. They can specialize in all cell types of the human body. However, their differential potential may vary and can be classified into five types. Stem cells can be (1) Totipotent, (2) Pluripotent, (3) Multipotent, (4) Oligopotent, and (5) Unipotent. Each stem cell has a specific origin; the fertilized egg or zygote is a totipotent cell and...
Mesenchymal Stem Cells01:19

Mesenchymal Stem Cells

Mesenchymal stem cells (MSCs) are adult stem cells that can differentiate into most connective tissue cell types, except for hematopoietic cells, depending upon the source of MSCs. For example, bone-marrow-derived MSCs (BM-MSCs) can differentiate into osteocytes, hepatocytes, and pancreatic and neuronal cells. MSCs can be isolated from various sources such as bone marrow, placenta, adipose tissue, teeth, and Wharton’s jelly, a gelatinous substance in the umbilical cord. The ease of their access...
Tissue Renewal without Stem Cells01:23

Tissue Renewal without Stem Cells

After cellular or tissue damage, the resident stem cells present in the human body can locally repair and regenerate the damaged tissue or organ. However, even though some tissues do not have stem cells, they can repair and regenerate with the help of pre-existing cells. For example, beta cells of the pancreas and hepatocytes of the liver can divide to renew and regenerate the tissue. Here, both cell division and cell death are well regulated by homeostasis.
However, failure of such a system...
Clinical Applications of Epidermal Stem Cells01:19

Clinical Applications of Epidermal Stem Cells

Epidermal stem cells (EpiSCs) are mainly located at the basal layer of the epidermis. These cells repair minor injuries of the skin and replace dead skin cells. However, EpiSCs’ cannot heal severe wounds such as major burns or those from diabetes or hereditary disorders. In such cases, culturing the epidermal stem cells from the patient is possible and has yielded successful treatment options, such as laboratory-grown skin grafts. These grafts are synthesized using a patient’s own EpiSCs...

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Cellular Membrane Affinity Chromatography Columns to Identify Specialized Plant Metabolites Interacting with Immobilized Tropomyosin Kinase Receptor B
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Cellular Membrane Affinity Chromatography Columns to Identify Specialized Plant Metabolites Interacting with Immobilized Tropomyosin Kinase Receptor B

Published on: January 19, 2022

Botanical drugs and stem cells.

Po-Cheng Lin1, Li-Fu Chang, Po-Yen Liu

  • 1Department of Life Science and Graduate Institute of Biotechnology, National Dong Hwa University, Hualien, Taiwan.

Cell Transplantation
|October 5, 2010
PubMed
Summary

Chinese herbal medicine may regulate stem cell differentiation for regenerative medicine. This review explores herbs used for diseases like neurodegeneration and cardiovascular conditions, linking them to stem cell control.

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Area of Science:

  • Stem cell biology
  • Traditional Chinese Medicine
  • Regenerative Medicine

Background:

  • Stem cell differentiation is crucial for regenerative medicine.
  • Traditional Chinese Medicine (TCM) utilizes herbal remedies.
  • TCM herbs contain unique compounds with potential biological activity.

Purpose of the Study:

  • To review Chinese herbal medicines (CHMs) relevant to stem cell regulation.
  • To explore CHMs used in treating neurodegenerative, cardiovascular, and bone diseases.
  • To describe the interplay between CHMs and stem cell proliferation/differentiation.

Main Methods:

  • Literature review of scientific studies on CHMs and stem cells.
  • Analysis of traditional uses of herbs in treating specific diseases.
  • Synthesis of current research on CHM mechanisms in stem cell biology.

Main Results:

  • Certain CHMs show potential in modulating stem cell behavior.
  • Herbs used for neuronal, cardiovascular, and osteoporosis treatments may influence stem cells.
  • Evidence suggests CHMs can impact stem cell proliferation and differentiation pathways.

Conclusions:

  • CHMs represent a promising area for discovering novel stem cell regulators.
  • Further research is needed to elucidate specific compounds and mechanisms.
  • CHMs could offer new therapeutic strategies in regenerative medicine.