Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Oxygen Delivering System I: Nasal Cannula and Face Mask01:26

Oxygen Delivering System I: Nasal Cannula and Face Mask

The human body requires oxygen to function, and when the natural process of respiration is hindered, external devices, including the following, are needed to help deliver this vital gas.
Nasal Cannula
A nasal cannula is a lightweight tube split at one end into two prongs and placed in the nostrils. It is typically used to deliver low to medium levels of oxygen.
Suggested flow rate: The suggested flow rate for a nasal cannula typically ranges between 1 and 6 L/min.
Oxygen percentage setting:...
Administering Oxygen by Nasal Cannula01:29

Administering Oxygen by Nasal Cannula

Oxygen therapy is critical to patient care, especially for those struggling with respiratory issues. This intervention increases the oxygen concentration in the lungs, enhancing the amount of oxygen transported to the body's tissues. One standard method of delivering supplemental oxygen is through a nasal cannula, a non-invasive device that provides low to medium oxygen concentrations.
Nasal Cannulas
A nasal cannula is a lightweight tube split into two prongs placed in the nostrils, connected...
Oxygen Delivering System II: Venturi Mask and Transtracheal Oxygen01:16

Oxygen Delivering System II: Venturi Mask and Transtracheal Oxygen

Oxygen therapy is a pivotal aspect of medical care, particularly for patients with respiratory ailments. Two prominent oxygen-delivering systems include the Venturi mask and the transtracheal oxygen catheter.
Venturi Mask
The Venturi mask, named after the Venturi effect, is designed to deliver precise oxygen concentrations. It consists of a large tube with an oxygen inlet that narrows down, causing a pressure drop that pulls air in through adjustable side ports. The mask is a lightweight,...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Hybrid Nanoporous Gold-Cyclodextrin Nanosponge Platforms for Enhanced Model Contaminant Detection.

ACS applied polymer materials·2026
Same author

Correction: Tonon et al. 5-Azacytidine Downregulates the Proliferation and Migration of Hepatocellular Carcinoma Cells In Vitro and In Vivo by Targeting miR-139-5p/ROCK2 Pathway. <i>Cancers</i> 2022, <i>14</i>, 1630.

Cancers·2026
Same author

Trends in Inhibitors, Structural Modifications, and Structure-Function Relationships of Phosphodiesterase 4: A Review.

Biomolecules·2026
Same author

pH-Sensitive Dextrin-Based Nanosponges Crosslinked with Pyromellitic Dianhydride and Citric Acid: Swelling, Rheological Behavior, Mucoadhesion, and In Vitro Drug Release.

Gels (Basel, Switzerland)·2026
Same author

Redox responsive cyclodextrin-based drug delivery systems: a special insight to glutathione responsive CD-nanosponges.

Expert opinion on drug delivery·2026
Same author

Erratum to "Gemcitabine-loaded ICOS-Fc decorated nanosponges: a new chemo immunotherapy combination against pancreatic cancer". [Int. J. Pharm. 682 (2025) 125869].

International journal of pharmaceutics·2026

Related Experiment Video

Updated: Jun 8, 2026

Synthesis, Hemoglobin Encapsulation and Biorthogonal PEGylation in Hierarchically Porous UiO-66 Nanoparticles for Oxygen Delivery Applications
09:24

Synthesis, Hemoglobin Encapsulation and Biorthogonal PEGylation in Hierarchically Porous UiO-66 Nanoparticles for Oxygen Delivery Applications

Published on: May 8, 2026

Nanosponge formulations as oxygen delivery systems.

Roberta Cavalli1, Ansari Khalid Akhter, Agnese Bisazza

  • 1Dip. di Scienza e Tecnologia del Farmaco, Università degli Studi di Torino, via P. Giuria 9, I-10125, Torino, Italy. roberta.cavalli@unito.it

International Journal of Pharmaceutics
|October 5, 2010
PubMed
Summary

Cyclodextrin nanosponges were developed as novel oxygen delivery systems. These nanoparticles demonstrate potential for controlled oxygen release, offering a promising platform for gas delivery applications.

More Related Videos

Nanosponge Tunability in Size and Crosslinking Density
11:15

Nanosponge Tunability in Size and Crosslinking Density

Published on: August 4, 2017

Designing Porous Silicon Films as Carriers of Nerve Growth Factor
10:12

Designing Porous Silicon Films as Carriers of Nerve Growth Factor

Published on: January 25, 2019

Related Experiment Videos

Last Updated: Jun 8, 2026

Synthesis, Hemoglobin Encapsulation and Biorthogonal PEGylation in Hierarchically Porous UiO-66 Nanoparticles for Oxygen Delivery Applications
09:24

Synthesis, Hemoglobin Encapsulation and Biorthogonal PEGylation in Hierarchically Porous UiO-66 Nanoparticles for Oxygen Delivery Applications

Published on: May 8, 2026

Nanosponge Tunability in Size and Crosslinking Density
11:15

Nanosponge Tunability in Size and Crosslinking Density

Published on: August 4, 2017

Designing Porous Silicon Films as Carriers of Nerve Growth Factor
10:12

Designing Porous Silicon Films as Carriers of Nerve Growth Factor

Published on: January 25, 2019

Area of Science:

  • Biomaterials Science
  • Nanotechnology
  • Drug Delivery Systems

Background:

  • Cyclodextrins are cyclic oligosaccharides with a hydrophobic cavity and hydrophilic exterior.
  • Nanosponges are cross-linked cyclodextrin nanoparticles, previously explored as drug carriers.
  • Controlled oxygen delivery remains a challenge in various medical and industrial applications.

Purpose of the Study:

  • To synthesize and characterize cyclodextrin nanosponges (α, β, γ) for oxygen delivery.
  • To evaluate the oxygen loading, release kinetics, and safety of these nanosponge formulations.
  • To assess the potential of nanosponges in facilitating oxygen permeation.

Main Methods:

  • Synthesis of α, β, and γ cyclodextrin nanosponges using carbonyldiimidazole cross-linking.
  • In vitro saturation of nanosponges with oxygen and characterization of their properties.
  • Cytotoxicity assessment of nanosponges using Vero cells.
  • Oxygen release studies in the presence and absence of ultrasound (US).
  • Evaluation of oxygen permeation through a silicone membrane using a β-cyclodextrin nanosponge/hydrogel system.

Main Results:

  • Three types of cyclodextrin nanosponges were successfully synthesized.
  • Nanosponges demonstrated the capacity to be saturated with oxygen.
  • In vitro studies showed sustained oxygen release over time, influenced by ultrasound.
  • Nanosponge formulations exhibited safety in Vero cell assays.
  • A β-cyclodextrin nanosponge/hydrogel system facilitated oxygen permeation.

Conclusions:

  • Cyclodextrin nanosponges are viable carriers for oxygen storage and controlled release.
  • The developed nanosponge formulations show potential as effective gas delivery systems.
  • Ultrasound may modulate oxygen release kinetics from nanosponge systems.
  • These nanosponges represent a promising advancement in oxygen delivery technology.