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Related Concept Videos

Imaging Biological Samples with Optical Microscopy01:18

Imaging Biological Samples with Optical Microscopy

Optical microscopy uses optic principles to provide detailed images of samples. Antonie van Leeuwenhoek designed the first compound optical microscope in the 17th century to visualize blood cells, bacteria, and yeast cells. In 1830, Joseph Jackson Lister created an essentially modern light microscope. The 20th century saw the development of microscopes with enhanced magnification and resolution.
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The early pioneers of microscopy opened a window into the invisible world of microorganisms. In 1830, Joseph Jackson Lister created an essentially modern light microscope. The 20th century saw the development of microscopes that leveraged nonvisible light, such as fluorescence microscopy that uses an ultraviolet light source and electron microscopy that uses short-wavelength electron beams. These advances significantly improved magnification, image resolution, and contrast. By comparison, the...

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Software tools for molecular microscopy: an open-text Wikibook.

Neil R Voss1, Clinton S Potter, Ross Smith

  • 1The National Resource for Automated Molecular Microscopy, Department of Cell Biology, The Scripps Research Institute, La Jolla, California, USA.

Methods in Enzymology
|October 5, 2010
PubMed
Summary
This summary is machine-generated.

A new Wikibook offers a comprehensive, community-updated list of cryo-electron microscopy (cryo-EM) software packages. This open-content resource aims to centralize and maintain essential tools for the cryo-EM field.

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Area of Science:

  • Biophysics and structural biology
  • Computational biology and bioinformatics

Background:

  • The cryo-electron microscopy (cryo-EM) field relies on a diverse and rapidly evolving set of software tools.
  • Discoverability and accessibility of these software packages can be challenging for researchers.
  • A centralized, community-driven resource is needed to track and maintain information on cryo-EM software.

Purpose of the Study:

  • To introduce a novel Wikibook resource dedicated to cataloging software relevant to cryo-EM.
  • To provide a comprehensive and continuously updated overview of available cryo-EM software tools.
  • To encourage community engagement in populating and refining the software list.

Main Methods:

  • Establishment of an open-content Wikibook platform.
  • Initial compilation of a snapshot of current cryo-EM software packages.
  • Community-driven content contribution, correction, and updating model.

Main Results:

  • A foundational Wikibook has been created, serving as a centralized repository for cryo-EM software.
  • The Wikibook provides an accessible overview of the current software landscape for the cryo-EM community.
  • The platform is designed for ongoing expansion and refinement through user contributions.

Conclusions:

  • The Wikibook represents a valuable, dynamic resource for the cryo-EM community.
  • Community participation is crucial for the long-term success and comprehensiveness of the software list.
  • This initiative aims to streamline software discovery and utilization in cryo-EM research.