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Updated: Jun 8, 2026

Flexible Colonoscopy in Mice to Evaluate the Severity of Colitis and Colorectal Tumors Using a Validated Endoscopic Scoring System
Published on: October 16, 2013
Advanced systems to assess colonoscopy
1Division of Gastroenterology and Hepatology, Department of Internal Medicine, Mayo Clinic College of Medicine, 200 First Street SW, Rochester, MN 55905, USA. pcdegroen@hotmail.com
Abstract:
Colorectal cancer is the second major cause of cancer-related death in the United States. The long time involved in progression of mucosal dysplasia from a small polyp to an invasive cancer and the ability to image the colon mucosa are features that make early detection and prevention of colorectal cancer by colonoscopy possible. Although colonoscopy has contributed to a marked decline in the number of colorectal cancer-related deaths, the protective effect of colonoscopy, when used in routine clinical practice, has not lived up to the expectations raised by carefully controlled prospective research studies. Therefore new systems that assess quality of colonoscopy are needed.
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