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Updated: Jun 8, 2026

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Granulocyte-dependent Autoantibody-induced Skin Blistering
Published on: October 12, 2012
Bullous pemphigoid after boiling water burn
Claude Bachmeyer1, Aurélie Cabanne-Hamy, Philippe Moguelet
1Service de Médecine Interne and Service d'Anatomopathologie, CHU Tenon (AP-HP), Paris, France. claude.bachmeyer@tnn.aphp.fr
Southern Medical Journal
|October 5, 2010
Summary
Bullous pemphigoid, a common autoimmune blistering disease, can be triggered by burns. This case shows bullous pemphigoid developing after a boiling water burn, initially localized to the burn site.
Area of Science:
- Dermatology
- Autoimmune diseases
- Blistering disorders
Background:
- Bullous pemphigoid (BP) is the most common autoimmune blistering disease.
- It typically affects elderly individuals and is often idiopathic.
- Understanding triggers for BP is crucial for patient management.
Observation:
- A case of bullous pemphigoid is presented.
- The condition developed four weeks subsequent to a boiling water burn.
- Initial lesions appeared at the burn site before generalizing.
Findings:
- This report details a rare instance of burn-induced bullous pemphigoid.
- The temporal and spatial association suggests a potential causal link.
- The findings highlight non-idiopathic presentations of bullous pemphigoid.
Implications:
- Trauma, such as burns, may act as a trigger for bullous pemphigoid.
- This expands the differential diagnosis for blistering lesions post-burn.
- Further research into burn-induced autoimmunity is warranted.
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