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Updated: Jun 8, 2026

Lateral Molar Approach-Driven Transoral Endoscopic Procedure for Benign Infratemporal Fossa Tumor Resection
Published on: August 15, 2025
Combined transnasal and transoral endoscopic approaches to the craniovertebral junction
Ivan H El-Sayed1, Jau-Ching Wu, Christopher P Ames
1Department of Otololaryngology-Head and Neck Surgery, UCSF Spine Center, University of California, San Francisco, San Francisco, USA.
Objectives:
To describe and evaluate a new technique of a combined endoscope-assisted transnasal and transoral approach to decompress the craniovertebral junction.
Materials And Methods:
A retrospective cohort of patients requiring an anterior decompression at the craniovertebral junction over a 12-month period was studied. Eleven patients were identified and included in the study. Eight of the patients had an endoscopic approach [endonasal (2), endooral (2), and combined (4)]. Four of the 8 patients in the endoscopic group had a prior open transoral procedure at other institutions. These 8 patients were compared with a contemporary group of 3 patients who had an open, transoral-transpalatal approach. Charts, radiographic images, and pathologic diagnosis were reviewed. We evaluated the following issues: airway obstruction, dysphagia, velopharyngeal insufficiency (VPI), length of hospital stay (LOS), adequate decompression, and the need for revision surgery.
Results:
Adequate anterior decompression was achieved in all the patients. The endoscopic cohort had a reduced LOS (P = 0.014), reduced need for prolonged intubation/tracheotomy (P =0.024) and a trend toward reduced VPI (P = 0.061) when compared with the open surgery group. None of the patients required a revision surgery.
Conclusion:
Proper choice of endoscopic transnasal, transoral, or combined approaches allows anterior decompression at the craniovertebral junction, while avoiding the need to split the palate. A combined transnasal-transoral approach appears to reduce procedure-related morbidity compared with open, transoral, and transpalatal surgeries.
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