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Stability of a novel dithranol ointment formulation, containing ascorbyl palmitate as an anti-oxidant
P J Weller1, C M Newman, K R Middleton
1Pharmacy Department, Northwick Park Hospital, Harrow, Middlesex, U.K.
Journal of Clinical Pharmacy and Therapeutics
|December 1, 1990
Abstract:
An emulsifying ointment-based dithranol formulation is described which was, with the addition of 0.1% w/w ascorbyl palmitate, stable for 52 weeks at room temperature. This is in contrast to the more conventionally used dithranol in Lassar's paste, which is stable for only 4 weeks at room temperature. An emulsifying ointment-based paste was additionally more convenient to use since it was easier to apply and remove.