Related Experiment Video

Updated: Jun 8, 2026

Analysis of 18FDG PET/CT Imaging as a Tool for Studying Mycobacterium tuberculosis Infection and Treatment in Non-human Primates
10:04

Analysis of 18FDG PET/CT Imaging as a Tool for Studying Mycobacterium tuberculosis Infection and Treatment in Non-human Primates

Published on: September 5, 2017

Atypical presentation of Mycobacterium tuberculosis in an infant

D R Gayathri Devi1, Mangala Gowri, S Padmalatha

  • 1M.S Ramaiah Medical College, Bangalore, Karnataka, India. gayathri_devi2006@rediffmail.com

Indian Journal of Pediatrics
|October 5, 2010
PubMed

Insights

Skeletal muscle tuberculosis is a rare condition often diagnosed late, leading to permanent limb damage. Early detection and treatment with anti-tubercular drugs are crucial for successful outcomes in children.

Area of Science:

  • Orthopedics
  • Infectious Diseases
  • Pediatrics

Background:

  • Tuberculosis (TB) primarily affects the lungs, but skeletal muscle involvement is exceptionally rare.
  • Delayed diagnosis of extrapulmonary TB, including muscular TB, can result in severe functional impairment and deformities.

Observation:

  • A case study of a healthy child presenting with an intramuscular cystic swelling above the elbow.
  • Pus aspirated from the swelling contained acid-fast bacilli, consistent with Mycobacterium tuberculosis.

Findings:

  • Microbiological culture confirmed the presence of Mycobacterium tuberculosis in the aspirated pus.
  • The child received a successful course of anti-tubercular therapy.

Implications:

  • Highlights the importance of considering rare presentations of tuberculosis in pediatric cases.
  • Emphasizes the need for prompt diagnosis and treatment to prevent long-term sequelae of skeletal muscle TB.
  • Suggests that early intervention can lead to complete recovery and restoration of limb function.

More Related Videos

Intradermal Inoculation of Mycobacterium avium in the Mouse Ear09:20

Intradermal Inoculation of Mycobacterium avium in the Mouse Ear

Published on: July 3, 2025

Related Concept Videos

Atypical Pneumonia01:14

Atypical Pneumonia

Atypical pneumonia, often caused by Mycoplasma pneumoniae, is a form of pulmonary infection that differs from the classical presentation of bacterial pneumonia in both its cause and clinical symptoms. Mycoplasma pneumoniae is a pleomorphic bacterium notable for its lack of a rigid cell wall. This structural characteristic imparts resistance to beta-lactam antibiotics and significantly influences the bacterium’s behavior within the human host.Other pathogens responsible for the disease include...
Pulmonary Tuberculosis II01:28

Pulmonary Tuberculosis II

Tuberculosis, or TB, is a bacterial infectious disease caused by Mycobacterium tuberculosis. While its primary impact is on the lungs, leading to pulmonary tuberculosis, it can also affect various other organs, a condition referred to as extrapulmonary tuberculosis.
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
Tuberculosis01:23

Tuberculosis

Tuberculosis (TB) remains a significant global health concern, primarily targeting the lungs and spreading through airborne transmission. Infection begins when aerosolized droplet nuclei, expelled by an individual with active TB, are inhaled by another person. These microscopic particles carry Mycobacterium tuberculosis, the causative agent of TB. Upon reaching the alveoli, the bacilli are engulfed by alveolar macrophages. However, due to their specialized lipid-rich cell wall, these pathogens...
Pulmonary Tuberculosis III01:31

Pulmonary Tuberculosis III

Tuberculosis (TB) is a contagious infection primarily affecting the lung parenchyma but which can also affect other body parts. TB can be classified based on disease development, presentation, and the affected anatomical site.
The first classification is based on the development of the disease, and it includes the following categories:
Pulmonary Tuberculosis I01:29

Pulmonary Tuberculosis I

Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
Pulmonary Tuberculosis IV01:26

Pulmonary Tuberculosis IV

Tuberculosis, more commonly referred to as TB, is an infectious disease stemming from Mycobacterium tuberculosis. While it primarily impacts the lungs, TB can also affect other body areas. Given its severity and global impact, timely and accurate diagnosis is crucial for controlling its spread and improving patient outcomes.
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...