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Protocol for Dengue Infections in Mosquitoes (A. aegypti) and Infection Phenotype Determination
15:25

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Published on: July 4, 2007

Clinico-epidemiological profile of children hospitalized with dengue

Manjunath J Kulkarni1, Vijaya Sarathi, Vikas Bhalla

  • 1Department of Pediatrics, Sir Padampat Mother and Child Health Institute, SMS Medical College, Jaipur, Rajasthan, India.

Indian Journal of Pediatrics
|October 5, 2010
PubMed

Insights

This study highlights that children aged 6-12 years, particularly from urban areas, are most vulnerable to dengue illness. Dengue fever with bleeding (DFB) and epistaxis were common, with severe thrombocytopenia increasing bleeding risk.

Area of Science:

  • Pediatrics
  • Infectious Diseases
  • Epidemiology

Background:

  • Dengue remains a significant global health concern, particularly affecting pediatric populations.
  • Understanding the clinico-epidemiological profile of dengue in children is crucial for effective management and public health strategies.

Purpose of the Study:

  • To elucidate the clinical and epidemiological characteristics of children hospitalized with dengue illness.
  • To identify risk factors and common manifestations in pediatric dengue cases.

Main Methods:

  • A prospective study was conducted on 948 children diagnosed with dengue illness.
  • Data collection occurred over a three-month period (September-November 2006) at a tertiary care center in Jaipur.
  • Clinical symptoms, bleeding manifestations, and laboratory findings, including thrombocytopenia, were analyzed.

Main Results:

  • The majority of cases (70.8%) were male, with the 6-12 year age group being most affected (45.8%).
  • Urban areas contributed two-thirds of the cases.
  • Dengue fever (DF) occurred in 58.3% and dengue hemorrhagic fever (DHF) in 41.7%. Dengue fever with bleeding (DFB) represented 32% of cases.
  • Epistaxis was the most frequent spontaneous bleeding (25%), and 44.5% of cases exhibited bleeding manifestations.
  • Severe thrombocytopenia was associated with increased bleeding, and the case fatality rate was 1.1%.

Conclusions:

  • Children aged 6-12 years from urban settings are disproportionately affected by dengue.
  • Dengue fever with bleeding (DFB) constitutes a significant proportion of pediatric dengue cases.
  • Severe thrombocytopenia is a key indicator for increased bleeding risk in children with dengue.
Abstract

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