Facilitation of protein biosynthesis by ginsenoside-Rb2 administration in diabetic rats
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1Department of Applied Biochemistry, Toyama Medical and Pharmaceutical University, Japan.
Abstract:
In streptozotocin-induced diabetic rats given 10 mg/day of ginsenoside-Rb2 for 3 days, there was no significant increase in the serum protein and albumin levels, whereas a significant increase in these parameters was found in rats given the ginsenoside-Rb2 for 6 days. When the state of protein biosynthesis was determined using [14C] leucine, significantly activated protein biosynthesis was found in rats given ginsenoside-Rb2 for 3 days, indicating the presence of an activated state of protein biosynthesis prior to the evident quantitative increase.