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Mycotic infection and the pediatric surgeon
1Department of Pediatric Surgery, Tel-Aviv Medical Center, Israel.
Abstract:
The incidence of major fungal infection in recent years has paralleled increasing use of immunosuppressive drugs, broad spectrum antibiotics and implantable catheters and prostheses. The pediatric surgeon encounters fungi as agents of perioperative infection and anatomic disease requiring surgical intervention. Clinical mycology is increasingly challenged by a wide spectrum of unfamiliar fungi, fungal infections and antimycotic drugs. An overview of the expanding role of surgical mycosis in children is presented.
Insights
Fungal infections are rising in children due to increased immunosuppression and medical devices. Pediatric surgeons face challenges with new fungi and treatments for surgical mycosis.
Area of Science:
- Pediatric surgery
- Clinical mycology
- Infectious diseases
Background:
- Major fungal infections have increased in parallel with the use of immunosuppressive drugs, broad-spectrum antibiotics, and implantable devices.
- Pediatric surgeons are increasingly encountering fungal infections as causes of perioperative complications and anatomical diseases requiring surgical intervention.
- The field of clinical mycology faces growing challenges due to a wider array of unfamiliar fungi, infections, and antifungal drugs.
Purpose of the Study:
- To provide an overview of the expanding role of surgical mycosis in pediatric patients.
- To highlight the challenges faced by pediatric surgeons and clinical mycologists in managing fungal infections.
- To discuss the implications of increased immunosuppression and medical device use on pediatric surgical mycosis.
Main Methods:
- Literature review of recent trends in pediatric fungal infections.
- Analysis of clinical cases encountered by pediatric surgeons.
- Review of current diagnostic and therapeutic approaches in clinical mycology.
Main Results:
- A significant increase in the incidence of major fungal infections in children.
- Identification of specific risk factors including immunosuppressive therapy and indwelling devices.
- Recognition of a broadening spectrum of fungal pathogens and the complexities of treatment.
Conclusions:
- Surgical mycosis in children is an expanding and complex clinical problem.
- Effective management requires collaboration between pediatric surgeons and clinical mycologists.
- Continued research and development of antifungal therapies are crucial for improving outcomes.