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Updated: Aug 12, 2026

Murine Precision-Cut Liver Slices as an Ex Vivo Model of Liver Biology
Published on: March 14, 2020
[Peptic ulcer in liver cirrhosis]
A Giacobbe1, D Facciorusso, P Conoscitore
1Divisione di Gastroenterologia ed Endoscopia Digestiva, Ospedale Generale Regionale, Casa Sollievo della Sofferenza di San Giovanni Rotondo (Foggia).
Abstract:
The frequency of peptic ulcer and the role of ulcerogenic risk factors in cirrhotic patients were evaluated in a retrospective study. Peptic disease was observed in 18.2% of the cirrhotic patients examined. When compared to the prevalence of ulcerative lesions in the general population, this finding suggests that cirrhotic patients have the same probability of being affected by peptic ulcer as non-cirrhotic subjects. The analysis of ulcerogenic risk factors highlighted the importance of alcohol and smoking. The etiology of cirrhosis and portal hypertension were not found to be important. In conclusion, peptic disease is not more frequent in cirrhotic patients than in the general population.
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