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Recombinant human gamma-interferon in primary hepatocellular carcinoma

W Shiu1

  • 1Department of Clinical Oncology, Chinese University of Hong Kong.

Journal of the Royal Society of Medicine
|October 5, 2010
PubMed
Summary

No abstract available in PubMed .

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Protein synthesis is indispensable for viral replication, as viruses lack the cellular machinery required for this process and must hijack the host's translational apparatus. In response, host cells deploy a critical innate immune defense involving interferons, specialized cytokines that play a central role in inhibiting viral propagation.Upon viral detection, infected cells release interferons that bind to receptors on adjacent uninfected cells, activating the JAK-STAT signaling pathway and...

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