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Biological properties of staphylococcal lipoteichoic acid and related macromolecules
1Department of Microbiology, St. Marianna University School of Medicine, Kawasaki, Japan.
Abstract:
Lipoteichoic acids (LTAs) and related macromolecules (e.g. cell surface substance, CSS; cell surface antigen, CSA; cell surface complex, CSC) are a group of phosphate-containing polymers associated with the cell walls of Gram-positive bacteria (32). They may be considered as surface-reactive antigens (immunogens, biological response modyfiers) as well as membrane components which mediate the attachment of certain bacteria (S. saprophyticus, S. aureus, group A streptococci) to host cell tissues.