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Updated: Aug 3, 2026

Directed Differentiation of Primitive and Definitive Hematopoietic Progenitors from Human Pluripotent Stem Cells
Published on: November 1, 2017
Hematopoietic growth factors and progenitor cells in human acute leukemia
B Löwenberg1, R Delwel, I Touw
1Dr. Daniel den Hoed Cancer Center, Rotterdam, The Netherlands.
Abstract:
In acute leukemia a neoplastic cell population escapes normal maturation impulses and expands selectively at the expense of normal hematopoiesis. How human acute leukemia cells react in the interplay of regulatory factors that control hematopoiesis and whether growth-factor abnormalities determine abnormal growth is only beginning to become evident. In this chapter developments resulting from the cloning of hematopoietic growth factors and the characterization of hematopoietic progenitor cells have been discussed.
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