Related Experiment Videos
Aetiology of bacterial diarrhoea in north Indian children with special reference to Campylobacter jejuni
Insights
This study investigated 184 young children with acute diarrhea, finding enteropathogens in 22.28% of cases. Most bacterial isolates showed sensitivity to gentamicin and cephaloridine, with low rates of secondary lactose intolerance.
Area of Science:
- Pediatric Infectious Diseases
- Clinical Microbiology
- Gastroenterology
Background:
- Acute diarrhea remains a significant health concern in infants and young children.
- Identifying causative enteropathogens is crucial for effective treatment and management.
- Understanding antimicrobial susceptibility patterns is essential for guiding therapy.
Purpose of the Study:
- To determine the prevalence of enteropathogens in children under 36 months with acute diarrhea.
- To analyze the antimicrobial susceptibility of common bacterial isolates.
- To assess the incidence of secondary lactose intolerance.
Main Methods:
- Clinicobacteriological study of 184 pediatric cases of acute diarrhea.
- Isolation and identification of enteropathogens.
- Antimicrobial susceptibility testing using gentamicin and cephaloridine.
- Clinical assessment for secondary lactose intolerance.
Main Results:
- Enteropathogens were identified in 22.28% of cases.
- Salmonella species, particularly S. typhimurium, were frequently isolated (7.6%).
- Over 75% of Salmonella, Shigella, E. coli, and Campylobacter jejuni isolates were sensitive to gentamicin and cephaloridine.
- Secondary lactose intolerance was observed in 6.52% of patients.
Conclusions:
- Enteropathogens are present in a notable proportion of acute diarrhea cases in young children.
- Commonly isolated pathogens show good susceptibility to gentamicin and cephaloridine.
- Secondary lactose intolerance is relatively uncommon in this cohort.
Abstract:
A total of 184 cases of acute diarrhoea, in patients aged 1-36 months, were studied clinicobacteriologically. Enteropathogens were isolated in 22.28% cases. Campylobacter jejuni was isolated from 2.17% cases only. Salmonellae were isolated from 7.6% cases and 64.28% of them were S typhimurium. More than 75% of all isolates of salmonellae, shigellae, Esch coli and Campylobacter jejuni were sensitive to gentamicin and cephaloridine. Secondary lactose intolerance was noted in 6.52% cases only.