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Updated: Aug 10, 2026

Primary Orthotopic Glioma Xenografts Recapitulate Infiltrative Growth and Isocitrate Dehydrogenase I Mutation
Published on: January 14, 2014
[Intracerebral gangliocytoma: a histological and immunohistochemical study]
E Roselló Sastre1, M Cerda Nicolás, C Barcia Mariño
1Departamento de Patología Neuropatología, Facultad de Medicina, Valencia.
Abstract:
We present a case of cerebral gangliocytoma placed on the right frontal lobe in a young adult, analyzing its morphological and clinical features. The immunohistochemical study defines it as a tumor with a neuronal population NSE and NFP positive, and a glial population with positivity for the GFAP. We emphasize the presence of neurosecretion in the mature neurones, typified by the positivity to the sinaptophisine and VIP. In the discussion we compare our immunohistochemical results, analyzing the histogenesis of this rare neoplasm.

