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Improved Renal Denervation Mitigated Hypertension Induced by Angiotensin II Infusion
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Improved Renal Denervation Mitigated Hypertension Induced by Angiotensin II Infusion

Published on: May 26, 2022

[Diagnosis and choice of therapy of arterial hypertension]

E E Gogin

    Klinicheskaia Meditsina
    |October 6, 2010
    PubMed

    Insights

    This study explores hypertensive disease development, discussing pathogenesis, therapy impacts, and cardiovascular regulation from fetal life to aging. It proposes diagnostic algorithms and prevention strategies for hypertension and related disorders.

    Area of Science:

    • Cardiovascular Medicine
    • Hypertension Research
    • Physiology

    Context:

    • Hypertensive disease involves complex pathogenesis and clinical evolution.
    • Understanding hemodynamics and angiogenesis is crucial from fetal development through involution.
    • Environmental factors significantly influence cardiovascular processes.

    Purpose:

    • To expound the clinical concept of hypertensive disease using recent basic research.
    • To analyze the influence of symptomatic and pathogenetic therapies on clinical features.
    • To present physiological mechanisms of hemodynamics and angiogenesis regulation.

    Summary:

    • Discusses main stages of pathogenesis, complication risks, and comorbidities of hypertensive disease.
    • Analyzes hemodynamic regulation and angiogenesis from fetal life to involution.
    • Proposes differential diagnosis algorithms and therapeutic strategies for hypertension.

    Impact:

    • Provides insights into the development and management of hypertensive disease.
    • Highlights the role of therapy in modifying clinical features and preventing complications.
    • Offers a review of hypertensive disease distribution and prophylactic measures in developed countries.

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