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Updated: Jun 8, 2026
07:16
DNAzyme 10-23 - Based Nanomachines for Nucleic Acid Recognition
Published on: February 9, 2024
Chromene "lock", thiol "key", and mercury(II) ion "hand": a single molecular machine recognition system
Fang-Jun Huo1, Yuan-Qiang Sun, Jing Su
1Research Institute of Applied Chemistry, and Key Laboratory of Chemical Biology and Molecular Engineering of Ministry of Education, Shanxi University, Taiyuan, 030006, China.
Organic Letters
|October 6, 2010
Abstract:
A regenerative, molecular machine-like "ON-OFF-ON" chemosensor based on a chromene molecule with the pyran ring "OFF-ON-OFF" cycle is reported for the first time. It behaves as a molecular lock that requires a thiol "key" to open the lock and a mercury(II) ion "hand" that unlatches the key for unsheathing the key to close the lock.
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